ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li +25 more
wiley +1 more source
Reciprocal intern-nurse shadowing program may lead to improved interprofessional collaboration. [PDF]
Starnes LS +5 more
europepmc +1 more source
Ultra‐flexible electrodes composed of single‐walled carbon nanotubes on a polymeric substrate exhibit excellent transparency, water resistance, and conformability to hairy surfaces. These non‐invasive nanofilms are easily pierced by trichomes, overcoming the structural barriers in plant electrophysiology.
Yusuke Hori +3 more
wiley +1 more source
SDC-YOLOv8: An Improved Algorithm for Road Defect Detection Through Attention-Enhanced Feature Learning and Adaptive Feature Reconstruction. [PDF]
Yang H, Song Y, Liang Y, Tang E, Cao D.
europepmc +1 more source
Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang +15 more
wiley +1 more source
Case Report: POEMS syndrome secondary to multiple solitary plasmacytomas complicated by hypertriglyceridemia. [PDF]
Chen W +5 more
europepmc +1 more source
A deep comprehension of biomolecular phenomena at interfaces is significant with their fundamental and practical importance. Our experimental and theoretical investigations reveal that specific amino acids (glutamic acid and aspartic acid) exhibit an orientational coupling with liquid crystals, which can recognize and optically report the interfacial ...
Yena Choi +10 more
wiley +1 more source
Clinicopathological Analysis of 60 Cases of Pulmonary Cryptococcosis. [PDF]
Liu Q, Lei M.
europepmc +1 more source
Radiomics-based ultrasOund Model for differentiating Uterine Sarcomas from leiomyomas (ROMUS): a retrospective pilot Multicenter Italian Trials in Ovarian Cancer (MITO) study. [PDF]
Ciccarone F +23 more
europepmc +1 more source

