Results 51 to 60 of about 107,797 (245)
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Lest We Forget: Covid-19, the Defense Production Act, and Executive Order 13,917
Columbia Journal of Race and LawDuring his 2024 presidential campaign, Donald Trump claimed that the ongoing conflicts in Ukraine and Gaza would not have occurred had he been reelected in 2020.
N. Brock Enger
doaj +5 more sources
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Where Silence Becomes Suffering: Tackling Mental Health Stigma in Pakistan
Journal of the Dow University of Health SciencesIn the low and middle-income country (LMIC) context of South Asia, mental health continues to sit in the shadows, under-resourced, misunderstood, and often silenced.
Shunaiber Tauhid
doaj +3 more sources
A graceful multiversal link of particle physics to cosmology [PDF]
, 2007 In this paper we work out a multiverse scenario whose physical characteristics enable us to advance the following the conjecture that whereas the physics of particles and fields is confined to live in the realm of the whole multiverse formed by finite ...
A. Bloom +21 more
core +3 more sources
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
CAAI Transactions on Intelligence TechnologyAs an effective way to securely transfer secret images, secret image sharing (SIS) has been a noteworthy area of research. Basically in a SIS scheme, a secret image is shared via shadows and could be reconstructed by having the required number of them. A
Sara Charoghchi +2 more
doaj +1 more source
From Codes to Patterns: Designing Interactive Decoration for Tableware [PDF]
, 2013 We explore the idea of making aesthetic decorative patterns that contain multiple visual codes. We chart an iterative collaboration with ceramic designers and a restaurant to refine a recognition technology to work reliably on ceramics, produce a pattern
Ali, Shakir +7 more
core
Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source