Results 81 to 90 of about 6,712,581 (313)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The goal trumps the means: Highlighting goals is more beneficial than highlighting means in means‐end training [PDF]

open access: yes, 2013
Item does not contain fulltextMeans-end actions are an early-emerging form of problem solving. These actions require initiating initial behaviors with a goal in mind.
Woodward, Amanda L.   +5 more
core   +1 more source

Development of a Methodology Used to Predict the Wheel–Surface Friction Coefficient in Challenging Climatic Conditions

open access: yesFuture Transportation
This paper presents a novel methodology for predicting the tire–road friction coefficient in real-time under challenging climatic conditions based on a fuzzy logic inference system. The core innovation of the proposed approach lies in the integration and
Viktor V. Petin   +4 more
doaj   +1 more source

Evaluation Study of Labor Education in Order to Improving the Quality of Education in the Kutai Kartanegara East Kalimantan Province

open access: yesJurnal Bina Praja, 2015
Improving the quality of human resources is absolutely necessary in the process of education sector development in the era of globalization. The purpose of this study is; to evaluate the placement of education according to the competence, to analyze the ...
Muhammad Soleh Pulungan
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A new look at means on topological spaces

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1997
We use methods of algebraic topology to study when a connected topological space admits an n-mean map.
Peter Hilton
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Joint Ways and Means Committee sub-committee reports on budget appropriations, forty-eighth Legislative Assembly - 1955 [PDF]

open access: yes, 1955
Title from PDF cover (viewed on August 6, 2018)."Adopted by the Joint Committee."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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