Results 121 to 130 of about 8,161,217 (292)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
[Letter from Beth Reese Means to Bill McCarter and NTIEVA Members, July 11, 1994]
Photocopy of a letter from Beth Reese Means, Curator of Education for the Art Museum of South Texas, to Bill McCarter, co-director of North Texas Institute for Educators on the Visual Arts and NTIEVA Members.
Means, Beth Reese
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Means of preparation of students of humanitarian universities
The article presents the theoretical foundations and practical aspects of the use of modern means for the organization of the process of training students of humanitarian universities for professional activities, taking into account the formation of ...
Vera A. Кurina +2 more
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Words, Words, Words: Meanings, Meanings, Meanings! [PDF]
openaire +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Ways and Means co-chair principles for the second special session of 2020
Title from PDF caption (viewed on July 17, 2020).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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Certain Bounds for the Differences of Means [PDF]
Let Pn,r(x) be the generalized weighted power means. We consider bounds for the differences of means in the following forms(β = 0)
Peng Gao, Gao, Peng
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