Results 131 to 140 of about 6,712,581 (313)
Ends and means in conflict [PDF]
, 1987 journal articleA great danger of our time is our intense preoccupation with the ends we seek, so much so that we have overlooked the effect, usually and perhaps always the determinative effect, that our choice of means will have made upon the nature of ...
Firmage, Edwin B., Firmage, Edwin Brown
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
School Assessment in an inclusive education system – do we measure what we value or do we value what we can measure? [PDF]
This section will explain why we have focused on school-level assessment of inclusion. We will discuss different approaches to school assessment and how they can support inclusive practice in the light of diverse understandings of inclusion across ...
Chiou, Vana +3 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Monotonicity Results for Arithmetic Means of Concave and Convex Functions [PDF]
, 2006 By majorization approaches, some known results on monotonicity of the arithmetic means of convex and concave functions are proved and generalized once ...
Xu, Tie-Quan, Qi, Feng, Shi, Huan-Nan
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Effect analysis of payload variation on energy consumption of a hydrogen powered light urban train [PDF]
, 2019 In this study a light hybrid rail train hydrogen powered is considered and the influence of the payload factor variation on traction energy consumption is investigated.
Masciovecchio C., D'Ovidio G., Ometto A.
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Trade-Offs in Means Tested Pension Design [PDF]
Inclusion of means testing into age pension programs allows governments to better direct benefits to those most in need and to control funding costs by providing flexibility to control the participation rate (extensive margin) and the benefit level ...
Alan Woodland, Chung Tran
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