Results 231 to 240 of about 16,568,157 (301)

Independent and interactive effects of limestone solubility, dietary calcium content and phytase dose on growth performance, mineral digestibility and utilization in broilers. [PDF]

Poult Sci
Bello A, Kwakernaak C, Davin R, Santos RR, Marchal L, Dersjant-Li Y.   +5 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

A novel method based on clustering and decision-making for construction project portfolio selection. [PDF]

PLoS One
Khalilzadeh M, Taebi P, Heidari A.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Integrating machine learning techniques for critical node identification in complex networks. [PDF]

Sci Rep
ReddyPriya M, Enduri MK, Hajarathaiah K, Satish A, Bandaru N.   +4 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The Meaning of Meaning

, 2014
openaire   +3 more sources

Allelopathic and autotoxic effects of sorghum extract and residues on seed behavior, and morphological, physiological, and biochemical responses of several plants. [PDF]

Sci Rep
Shahmohammadi F, Abdi M, Faramarzi A, Ajalli J, Nourafcan H.   +4 more
europepmc   +1 more source

Correction: The influence of model building schemes and molecular dynamics sampling on QM-cluster models: the chorismate mutase case study.

Phys Chem Chem Phys
Agbaglo DA, Summers TJ, Cheng Q, DeYonker NJ.   +3 more
europepmc   +1 more source

Empowering Quality of Life Monitoring and Self-Management in Bipolar Disorder: Pilot Evaluation of the PolarUs App. [PDF]

Bipolar Disord
Michalak EE, Morton EE, Meyer D, Murray G, O Brien HL, Barnes SJ.   +5 more
europepmc   +1 more source