Results 101 to 110 of about 8,161,217 (292)

Ky Fan Inequality and Bounds for Differences of Means [PDF]

open access: yes, 2002
We prove an equivalent relation between Ky Fan-typed inequalities and certain bounds for the differences of means. We also generalize a result of H. Alzer, S.
Peng Gao, Gao, Peng, Peng Gao
core   +2 more sources

[Darwinism and the meaning of "meaning"].

open access: yesAsclepio; archivo iberoamericano de historia de la medicina y antropologia medica, 2009
The problem of the meaning of life is herewith contemplated from a Darwinian perspective. It is argued how factors such as existential depression, the concern about the meaning of ‘meaning’, the problem of evil, death as the end of our personal identity, happiness as an unachievable goal, etc. may well have an adaptive dimension ‘controlled’ neither by
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Comprehensive program of increase of efficiency of locomotive park JSC RZHD

open access: yesВестник СибАДИ, 2017
The authors propose a comprehensive program of unification into a single system all processes of the life cycle of locomotives that reduce costs associated primarily with the operation and maintenance of a locomotive fleet of JSC "Russian Railways".
P. N. Rubezhanski, A. V. Davydov
doaj  

Improvement of the organization of Federal contract system of purchases

open access: yesПутеводитель предпринимателя, 2020
In article questions and problems of a choice of reliable commercial partners are considered at implementation of purchases for the state and municipal structures of the goods and products, services and works. Offers on procedures, methods and approaches

doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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