Results 91 to 100 of about 6,712,581 (313)

[Reports to Senate Ways and Means Committee, Legislative Assembly, 1895] [PDF]

open access: yes, 1895
Manuscript and typescript.Title supplied by cataloger.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode

core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Kristin Norderval-Means, Senior Recital, March 5, 1983 [PDF]

open access: yes, 1983
Concert program for Kristin Norderval-Means, Senior Recital, March 5 ...

core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

On a Conjecture on the Symmetric Means [PDF]

open access: yes, 2006
In this paper, we study some inequalities involving the symmetric means. The main result is a proof of a conjecture of Alzer et al.
Gao, Peng
core  

Experimental Investigation and Performance Evaluation of Automated Emergency Braking (AEB) Systems Under Actual Driving Conditions

open access: yesVehicles
This paper presents an experimental study of the Automatic Emergency Braking (AEB) system, focusing on three essential testing phases: verifying the match between calculated and actual brake actuator operation time, validating the forecasted vs.
Viktor V. Petin   +4 more
doaj   +1 more source

Swimming as important factor of development of physical abilities [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012
The current state of health and physical fitness of young people, the complex of issues regarding the development of sports and mass swimming in Ukraine, in particular regarding training the ability to swim of the population and its conscripts have been ...
Popadin V.V.   +2 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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