Results 41 to 50 of about 390,420 (292)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Vented Individual Patient (VIP) Hoods for the Control of Infectious Airborne Diseases in Healthcare Facilities

Engineering, 2022
By providing a means of separating the airborne emissions of patients from the air breathed by healthcare workers (HCWs), vented individual patient (VIP) hoods, a form of local exhaust ventilation (LEV), offer a new approach to reduce hospital-acquired ...
J. Patel, F. McGain, T. Bhatelia, S. Wang, B. Sun, J. Monty, V. Pareek   +6 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Pervasive Computing, Privacy and Distribution of the Self

Information, 2011
The emergence of what is commonly known as “ambient intelligence” or “ubiquitous computing” means that our conception of privacy and trust needs to be reconsidered.
Soraj Hongladarom
doaj   +1 more source

WIRELESS WI-FI SECURITY ANALYSIS IN AUTOMATED RAILWAY SYSTEMS

Nauka ta progres transportu, 2020
Purpose. The article is aimed to analyze the basic security mechanisms available in Wi-Fi networks; show the mechanisms for attacking these defenses; carry out a comparative analysis of the effectiveness of protection mechanisms; provide recommendations ...
I. V. Zhukovyts’kyi, I. A. Pedenko
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Artificial Intelligence, the Internet of Everything and the Scope and Scale of Seduction at the Boundaries of Law

Public Governance, Administration and Finances Law Review
Online and algorithmic systems can promote the emotional, intellectual and political seduction of people. The power and scope of these systems may create new threats against which traditional means of protection may be overwhelmed.
Michael M. Losavio
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Innovative Industrial Technologies for Preventive Anti-Graffiti Coating

MATEC Web of Conferences, 2017
Graffiti is the main issue in terms of acts of vandalism with public transport. Hardly any suburban train, commuter train or goods train, hardly any engineering building, station or noise barrier wall escape graffiti spraying.
Heinisch Martin, Miricescu Dan
doaj   +1 more source