Results 61 to 70 of about 362,055 (276)

Criminal offenses against official duty with a focus on the object of the criminal offense

Pravo
The very title of the group of criminal offenses against official duty reveals their object of protection, which is the conscientious and responsible performance of official duties.
Mile Šikman, Velibor Bajičić
doaj   +1 more source

Soldier protection in the defence system against weapons of mass destruction [PDF]

Biuletyn Wojskowej Akademii Technicznej
This article addresses a very important and relevant issue of protecting the soldier on the modern battlefield. Military doctrinedocuments a lack information on individual soldier protection.
Władysław Harmata, Piotr Wachna
doaj   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Measuring the Effectiveness of Control Mechanisms in Regional Human Rights Systems – from Conception to Execution

Przegląd Prawno-Ekonomiczny
The lowest level of protection is ensured under the domestic law of individual countries. The aim of the article is to develop a methodology for measuring the effectiveness of control mechanisms functioning within regional human rights protection ...
Jarosław Kowalski
doaj   +1 more source

Effect of individual and community-level bed net usage on malaria prevalence among under-fives in the Democratic Republic of Congo

Malaria Journal, 2018
Background Understanding the contribution of community-level long-lasting, insecticidal net (LLIN) coverage to malaria control is critical to planning and assessing intervention campaigns.
Lauren Levitz, Mark Janko, Kashamuka Mwandagalirwa, Kyaw L. Thwai, Joris L. Likwela, Antoinette K. Tshefu, Michael Emch, Steven R. Meshnick   +7 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

A Multiagent Alphavirus DNA Vaccine Delivered by Intramuscular Electroporation Elicits Robust and Durable Virus-Specific Immune Responses in Mice and Rabbits and Completely Protects Mice against Lethal Venezuelan, Western, and Eastern Equine Encephalitis Virus Aerosol Challenges

Journal of Immunology Research, 2018
There remains a need for vaccines that can safely and effectively protect against the biological threat agents Venezuelan (VEEV), western (WEEV), and eastern (EEEV) equine encephalitis virus.
Lesley C. Dupuy, Michelle J. Richards, Brian D. Livingston, Drew Hannaman, Connie S. Schmaljohn   +4 more
doaj   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Readiness of senior higher school students for self-determination in ecology field as an ability to form subjective attitude

SHS Web of Conferences, 2016
The current state of environment demands from senior pupils to occupy a correct position in problem ecological situations. An effective means of forming senior pupils’ own position is activity in a field of ecology. Through a variety of activities in the
Titov Evgeny V., Cherkashin Evgeny I.
doaj   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source