Results 41 to 50 of about 258,439 (311)

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

The measles epidemic trend over the past 30 years in a central district in Shanghai, China.

PLoS ONE, 2017
BackgroundMeasles vaccination over the past 50 years has greatly reduced the incidence of measles. However, measles among migrants and the resulting changes in epidemiological characteristics have brought new challenges to the elimination of measles.
Jie Gao, Bing Shen, JianJing Xiong, Yihan Lu, Qingwu Jiang   +4 more
doaj   +1 more source

A Lesson from a Measles Outbreak among Healthcare Workers in a Single Hospital in South Korea: The Importance of Knowing the Prevalence of Susceptibility

Vaccines, 2023
Background: Despite the high vaccination coverage rate, in-hospital transmission of measles continues to occur in South Korea. We present a measles outbreak in which two healthcare workers (HCWs) with presumptive evidence of measles immunity were ...
Sungim Choi, Jae-Woo Chung, Yun Jung Chang, Eun Jung Lim, Sun Hee Moon, Han Ho Do, Jeong Hun Lee, Sung-Min Cho, Bum Sun Kwon, Yoon-Seok Chung, Seong Yeon Park   +10 more
doaj   +1 more source

Extracting the time-dependent transmission rate from infection data via solution of an inverse ODE problem [PDF]

, 2012
The transmission rate of many acute infectious diseases varies significantly in time, but the underlying mechanisms are usually uncertain. They may include seasonal changes in the environment, contact rate, immune system response, etc.
Anderson R. M., Becker N. G., Dowell S. F., Fujinami R. S., Hao Wang, Howard (Howie) Weiss, Keeling M. J., Kincaid D., Mark Pollicott, Mollison D., Yorke J. A.   +10 more
core   +1 more source

T2T Genomes Unveil Centromere Architecture and Adaptive Divergence in Large Yellow Croaker (Larimichthys crocea)

Advanced Science, EarlyView.
This study presents telomere‐to‐telomere genome assemblies for two populations of Larimichthys crocea. We identified centromere‐specific tandem repeats invaded by LTR/ERV1 retrotransposons, unique 5S rRNA enrichment patterns, and population‐specific structural variants. Comparative genomic analyses further reveal distinct adaptive mechanisms in the MYD
Yu Cui, Yingbo Yuan, Bi Wang, Baolan Wu, Mingyi Cai, Ming Fang, Weiliang Shen, Xiongfei Wu, Fang Han, Zhiyong Wang   +9 more
wiley   +1 more source

Vaccine-induced neutralizing antibodies bind to the H protein of a historical measles virus

International Journal of Medical Microbiology
Measles is a highly contagious airborne viral disease. It can lead to serious complications and death and is preventable by vaccination. The live-attenuated measles vaccine (LAMV) derived from a measles virus (MV) isolated in 1954 has been in use ...
Anne Zemella, Kerstin Beer, Franziska Ramm, Dana Wenzel, Ariane Düx, Kevin Merkel, Sebastien Calvignac-Spencer, Daniel Stern, Martin B. Dorner, Brigitte G. Dorner, Navena Widulin, Thomas Schnalke, Cornelia Walter, Anne Wolbert, Bernhard G. Schmid, Annette Mankertz, Sabine Santibanez   +16 more
doaj   +1 more source

A unique measles B3 cluster in the United Kingdom and the Netherlands linked to air travel and transit at a large international airport, February to April 2014 [PDF]

, 2016
Rita de Sousa (Bolseira EUPHEM) - Investigadora do Departamento de Doenças Infeciosas do Instituto Ricardo JorgeThis report describes a joint measles outbreak investigation between public health officials in the United Kingdom (UK) and the Netherlands ...
Brown, K.E., de Sousa, R., Hahné, S., Lochlainn, L.N., Mandal, S., Paranthaman, K., Ramsay, M., van Binnendijk, R.   +7 more
core   +1 more source

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

Advanced NanoBiomed Research, EarlyView.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez, Julio García‐Cordero, Gabriela Navarro‐Tovar, Leticia Cedillo‐Barrón   +3 more
wiley   +1 more source

Genetic characterization of measles virus circulating in Iran, 2021–2023

BMC Infectious Diseases
Background Measles, an ongoing public health concern, demands continuous molecular surveillance and virus characterization for elimination. Despite Iran achieving measles elimination status in 2019 through robust molecular testing and vaccination, the ...
Alireza Esmaeiloghli Amiryli, Simin Abbasi, Faezeh Tarpoor, Azadeh Shadab, Azam Saboori, Nazanin-Zahra Shafiei Jandaghi, Vahid Salimi, Talat Mokhtari-Azad   +7 more
doaj   +1 more source

The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]

, 2011
By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG, de Quadros, CA, Dowdle, WR, Foege, WH, Henderson, DA, John, TJ, Levine, MM   +6 more
core   +1 more source