Results 81 to 90 of about 689,691 (318)

Modeling and presentation of vaccination coverage estimates using data from household surveys [PDF]

, 2020
It is becoming increasingly popular to produce high-resolution maps of vaccination coverage by fitting Bayesian geostatistical models to data from household surveys. Often, the surveys adopt a stratified cluster sampling design. We discuss a number of crucial choices with respect to two key aspects of the map production process: the acknowledgment of ...
arxiv   +1 more source

The Antiviral Activity of Polyphenols

Molecular Nutrition &Food Research, EarlyView.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard, Alban Piotrowsky, Christian Leischner, Katja Detert, Sascha Venturelli, Luigi Marongiu   +5 more
wiley   +1 more source

High-Affinity DARPin Allows Targeting of MeV to Glioblastoma Multiforme in Combination with Protease Targeting without Loss of Potency

Molecular Therapy: Oncolytics, 2019
Measles virus (MeV) is naturally cytolytic by extensive cell-to-cell fusion. Vaccine-derived MeV is toxic for cancer cells and is clinically tested as oncolytic virus.
Jan R.H. Hanauer, Vivian Koch, Ulrich M. Lauer, Michael D. Mühlebach   +3 more
doaj  

Estimating efficacy of measles supplementary immunization activities via discrete-time modeling of disease incidence time series [PDF]

arXiv, 2020
Measles is a significant source of global disease burden and child mortality. Measles vaccination through routine immunization (RI) programs in high-burden settings remains a challenge due to poor health care infrastructure and access. Supplementary immunization activities (SIA) in the form of vaccination campaigns are therefore implemented to prevent ...
arxiv  

Adding interventions to mass measles vaccinations in India. [PDF]

, 2016
OBJECTIVE: To quantify the impact on mortality of offering a hypothetical set of technically feasible, high-impact interventions for maternal and child survival during India's 2010-2013 measles supplementary immunization activity.
Gauvreau, Cindy, Jha, Prabhat, Jit, Mark, Johri, Mira, Jones, Edward, Morris, Shaun K, Ram, Usha, Sharma, Jitendar K, Verguet, Stéphane   +8 more
core   +1 more source

A large population-based association study between HLA and KIR genotypes and measles vaccine antibody responses

PLoS ONE, 2017
Human antibody response to measles vaccine is highly variable in the population. Host genes contribute to inter-individual antibody response variation. The killer cell immunoglobulin-like receptors (KIR) are recognized to interact with HLA molecules and ...
I. Ovsyannikova, D. Schaid, Beth R Larrabee, I. Haralambieva, R. Kennedy, G. Poland   +5 more
semanticscholar   +1 more source

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

Pediatric Discovery, EarlyView.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao, Zhongying Yang, Yu He, Jianhua Wei, Luo Ren, Enmei Liu, Na Zang   +6 more
wiley   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Vaccination, life expectancy, and trust: Patterns of COVID-19 vaccination rates around the world [PDF]

arXiv, 2022
We estimate patterns of covariation between COVID-19 vaccination rates and a set of widely used indicators of human, social, and economic capital across 146 countries in July 2021 and February 2022. About 70% of the variability in COVID-19 vaccination rates worldwide can be explained by differences in the Human Development Index (HDI) and, specifically,
arxiv  

Validating child vaccination status in a demographic surveillance system using data from a clinical cohort study: evidence from rural South Africa [PDF]

, 2011
<p><b>Background:</b> Childhood vaccination coverage can be estimated from a range of sources. This study aims to validate vaccination data from a longitudinal population-based demographic surveillance system (DSS) against data from a ...
A Heywood, AA Parker, AJ Herbst, AK Koumare, B Zaba, BD Rice, BR Lee, C Tarwa, Demographic and Health Surveys, DT Dunn, E Bos, EP Armstrong, F Tanser, F Tanser, F Tanser, FQ Cui, HM Coovadia, J Ndirangu, James Ndirangu, M Hoque, M Otten, Marie-Louise Newell, N Siegfried, R Biellik, R Bland, RF Breiman, Ruth Bland, S Anand, T Bärnighausen, T Bärnighausen, T Bärnighausen, TC Mast, Till Bärnighausen, UNICEF, W Muhwava, WHO-UNICEF   +35 more
core   +3 more sources