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Virology Of Measles Virus

Journal of Infectious Diseases, 1994
Measles virus is the prototypic member of the Morbillivirus genus of the family Paramyxoviridae. The viral genomic RNA is single-stranded, nonsegmented, and of negative polarity and encodes six major structural proteins. The two viral transmembrane glycoproteins, the hemagglutinin and fusion proteins, are both required for virus-host cell membrane ...
W J, Bellini, J S, Rota, P A, Rota
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Variants of measles virus

Medical Microbiology and Immunology, 1974
When tested on Vero cells the Edmonston strain of measles virus contained a mixture of plaque variants and variants which produced different kinds of cytopathic effect under liquid culture. A persistently infected culture of HEp2 cells which was derived from the Edmonston virus yielded low titers of infectious virus and was temperature sensitive (Gould,
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Measles Virus and Otosclerosis

2007
Measles virus (MeV) might play an important role as an environmental stimulus in the etiopathogenesis of otosclerosis. Chronic inflammation was shown in morphologic investigations of otosclerotic foci and MeV N, P, and F proteins were detected within cells of the otosclerotic focus by immunohistochemical investigations. MeV RNA was extracted from fresh-
H P, Niedermeyer   +3 more
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The nature of measles virus

Archiv f�r die gesamte Virusforschung, 1965
Observations of the effect of halogen derivatives of deoxyuridine, known to affect the synthesis of deoxyviruses (DNA-containing viruses) show that measles virus replication is unaffected. This suggests that measles virus is a ribovirus (RNA-containing virus).
Atherton, J. G., Lam, K. S.K.
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Measles Virus and CD46

2008
Measles virus (MV) was isolated in 1954 (Enders and Peeble 1954). It is among the most contagious of viruses and a leading cause of mortality in children in developing countries (Murray and Lopez 1997; Griffin 2001; Bryce et al. 2005). Despite intense research over decades on the biology and pathogenesis of the virus and the successful development in ...
C, Kemper, J P, Atkinson
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Measles Virus in the Brain

Brain Research Bulletin, 1997
Measles virus can give three different forms of infections in the central nervous system. These are acute postinfectious encephalitis, acute progressive infectious encephalitis, and subacute sclerosing panencephalitis (SSPE). The postinfectious acute disease is interpreted to reflect an autoimmune reaction.
E, Norrby, K, Kristensson
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The neuraminidase of measles virus

Biochemical and Biophysical Research Communications, 1969
The agent of measles (rubeola) has been assumed to be a paramyxovirus on the basis of its electron microscopic appearance, its size, its sensitivity to ether and detergents, and the presence of hemagglutinin in the viral envelope. Thus far, however, the one attribute common to myxoviruses, namely neuraminidase, has not been described for measles virus.
C, Howe, E W, Newcomb, L T, Lee
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Measles virus RNA

Biochemical and Biophysical Research Communications, 1971
Abstract RNA has been isolated from measles virions which sediments with a coefficient of 52.2 S when compared with 50 S RNA from SV 5 virions.
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ISOLATION OF INFECTIOUS MEASLES VIRUS IN MEASLES ENCEPHALITIS

The Lancet, 1972
Abstract A 40-year-old man developed encephalitis 3 days after onset of acute measles. He died 6 weeks later. Histopathological findings were consistent with late type of post-infectious measles encephalitis. Direct inoculation of a homogenate of fresh brain tissue obtained at necropsy into susceptible tissue cultures produced no infectious virus ...
V, ter Meulen   +4 more
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Molecular Epidemiology of Measles Virus

Seminars in Virology, 1995
Genetic characterization of wild-type measles viruses provides a means to study the transmission pathways of the virus and is an essential component of laboratory-based surveillance. Laboratory-based surveillance for measles and rubella, including genetic characterization of wild-type viruses, is performed throughout the world by the WHO Measles and ...
P A, Rota   +2 more
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