Results 91 to 100 of about 33,406 (259)

Infinite measure preserving transformations with “mixing” [PDF]

open access: yesBulletin of the American Mathematical Society, 1963
Kakutani, S., Parry, W.
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Objectif ZAN (Zéro artificialisation nette) et territoires ruraux : du débat national à la parole d’acteurs locaux

open access: yesL'Espace Politique
The Zero Net Artificialization (ZAN) objective is designed to fight urban sprawl and preserve biodiversity and natural agricultural and forest areas. After 2050, ZAN will be effective, meaning that any new artificial surface will have to be compensated ...
Joachim Dendievel
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

CORPOREALITY IN THE AGE OF POSTHUMANISM: ANTAEISM AS A HUMAN PRACTICE OF ROOTEDNESS

open access: yesОсвітній дискурс
Relevance of the research. The beginning of the twenty-first century has been marked by radical transformations in the modes of human existence driven by the accelerated development of technologies, including bioengineering and genetic engineering. These
Denys Fen
doaj   +1 more source

ON MÖBIUS DISJOINTNESS FOR INFINITE MEASURE-PRESERVING TRANSFORMATIONS

open access: yesKyushu Journal of Mathematics
The property of `Möbius disjointess', asymptotic orthogonality of the classical Möbius function to an observable on a topological dynamical system, is studied in the setting of infinite measure-preserving systems. Disjointness is shown to not hold at almost all points in the class of continuous bounded integrable observables for an ergodic system, and ...
HIRAYAMA, Michihiro, KARAGULYAN, Davit
openaire   +2 more sources

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Algebraic Models for Measure Preserving Transformations [PDF]

open access: yesTransactions of the American Mathematical Society, 1968
Dinculeanu, Nicolae, Foiaș, Ciprian
openaire   +2 more sources

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