Results 31 to 40 of about 3,770,508 (245)

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille   +9 more
wiley   +1 more source

Fuzzy Region-Based Active Contours Driven by Weighting Global and Local Fitting Energy

open access: yesIEEE Access, 2019
Active contour model (ACM) has been a successful method for image segmentation. The existing ACMs poorly segment the images with intensity inhomogeneity or non-homogeneity, and the results highly depend on the initial position of the contour. To overcome
Jiangxiong Fang   +4 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

The Combined Effect of Obesity and Contraceptive Use on Pulmonary Embolism in Adolescent Females Residing in the United States

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley   +1 more source

mHealth in sub-Saharan Africa and Europe: A systematic review comparing the use and availability of mHealth approaches in sub-Saharan Africa and Europe

open access: yesDigital Health, 2023
Background mHealth can help with healthcare service delivery for various health issues, but there's a significant gap in the availability and use of mHealth systems between sub-Saharan Africa and Europe, despite the ongoing digitalization of the global ...
Genet Tadese Aboye   +3 more
doaj   +1 more source

Revisiting the measure of development: A critique of sustainametrics

open access: yesFrontiers in Sustainability, 2022
For sustainametrics to gain a firm ground as an effective concept, the meaning of development shall be revisited first without depending on any statistical measurement.
Go Okui, Shutaro Takeda
doaj   +1 more source

Measuring measurement: theory and practice

open access: yesNew Journal of Physics, 2009
Recent efforts have applied quantum tomography techniques to the calibration and characterization of complex quantum detectors using minimal assumptions. In this work we provide detail and insight concerning the formalism, the experimental and theoretical challenges and the scope of these tomographical tools.
Feito, Alvaro   +5 more
openaire   +3 more sources

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian   +13 more
wiley   +1 more source

PROTAGORAS: HER ŞEYİN ÖLÇÜSÜ İNSAN

open access: yesFelsefe Dünyası, 2022
“Her şeyin ölçüsü insandır” [ölçü-insan/homo mensura] deyiminin epistemik bir tespitten ziyade ahlaki bir buyruk gibi insan zihnini sarsan ama aynı zamanda insani tevazudan uzaklaştıran bir tınısı vardır.
Lokman Çilingir
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi   +10 more
wiley   +1 more source

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