Results 111 to 120 of about 14,437 (302)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Existence of Solutions for w-Weighted ψ-Hilfer Fractional Differential Inclusions of Order μ ∈ (1, 2) with Non-Instantaneous Impulses in Banach Spaces

Fractal and Fractional
In this research, we obtain the sufficient conditions that guarantee that the set of solutions for an impulsive fractional differential inclusion involving a w-weighted ψ-Hilfer fractional derivative, D0,tσ,v,ψ,w,of order μ∈(1,2), in infinite dimensional
Zainab Alsheekhhussain, Ahmad Gamal Ibrahim, Mohammed Mossa Al-Sawalha, Yousef Jawarneh   +3 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Convergence of pointed non-compact metric measure spaces and stability of Ricci curvature bounds and heat flows [PDF]

, 2015
Nicola Gigli, Andrea Mondino, Giuseppe Savaré   +2 more
openalex   +1 more source

Generalized group algebras and generalized measure algebras on non-discrete locally compact abelian groups [PDF]

, 2023
Jyunji Inoue, Sin‐Ei Takahasi
openalex   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

On the existence of solutions for fractional boundary valued problems with integral boundary conditions involving measure of non compactness

, 2020
Ahmed Hamrouni, Said Beloul
openalex   +1 more source

Duality and free measures in vector spaces, the spectral theory of actions of non-locally compact groups [PDF]

, 2017
A. M. Vershik
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A study on the solvability of fractional integral equation in a Banach algebra via Petryshyn's fixed point theorem

Journal of Taibah University for Science
This study focuses on the nonlinear fractional functional integral equation (FFIE) concerning the Riemann-Liouville operator. In certain weaker conditions, the authors demonstrate that the FFIE has a solution, which is defined within the Banach algebra ...
Sukanta Halder, Deepmala, Cemil Tunç
doaj   +1 more source