Results 161 to 170 of about 14,437 (302)

Monotone and boolean convolutions for non-compactly supported probability measures [PDF]

, 2009
Uwe Franz
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

SAKURA: a knowledge-guided approach to recovering important, rare signals from single-cell data. [PDF]

Genome Biol
Zhang Z, Chen J, Wu H, Li KY, Adams PD, Itkin-Ansari P, Yip KY.   +6 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Sharp Conditions for the BBM Formula and Asymptotics of Heat Content-Type Energies. [PDF]

Arch Ration Mech Anal
Gennaioli L, Stefani G.
europepmc   +1 more source

On fractional neutral integro-differential systems with state-dependent delay via Kuratowski measure of non-compactness in Banach spaces

, 2018
A. Anuradha, M. Mallika Arjunan
openalex   +2 more sources

Quantitative Concentration Inequalities for Empirical Measures on Non-compact Spaces [PDF]

, 2006
François Bolley, Arnaud Guillin, Cédric Villani   +2 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

A complex reciprocal translocation is linked to reduced gamete viability in a loose-bunch grapevine somatic variant. [PDF]

BMC Plant Biol
Alañón-Sánchez N, Ferradás Y, Bezrukov I, Weigel D, Carbonell-Bejerano P, Ibáñez J.   +5 more
europepmc   +1 more source

An approach to harmonic analysis on non-locally compact groups II: an invariant measure on groups of ordered type

, 2019
Raven Waller
openalex   +2 more sources