Results 81 to 90 of about 2,873,064 (342)

Kinetic Inductance and Penetration Depth of Thin Superconducting Films Measured by THz Pulse Spectroscopy

, 1993
We measure the transmission of THz pulses through thin films of YBCO at temperatures between 10K and 300K. The pulses possess a useable bandwidth extending from 0.1 -- 1.5 THz (3.3 cm^-1 -- 50 cm^-1).
A. C. Campbell, A. M. Neminsky, A. P. Litvinchuk, B. Mühlschlegel, C. J. Gorter, D. A. Bonn, D. E. Aspnes, D. Grischkowsky, H. U. Habermeier, H.-U. Habermeier, I. E. Trofimov, J. Annett, J. Halbritter, J. Kuhl, J. Lee, J. O. White, J. R. Schrieffer, M. C. Nuss, M. R. Beasley, M. Y. Frankel, N. Klein, P. Arberg, R. Buhleier, S. D. Brorson, S. M. Anlage, W. N. Hardy, Z. Ma   +26 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Influence of section depth on the structural behaviour of reinforced concrete continuous deep beams [PDF]

, 2007
YesAlthough the depth of reinforced concrete deep beams is much higher than that of slender beams, extensive existing tests on deep beams have focused on simply supported beams with a scaled depth below 600 mm.
Ashour, Ashraf, Yang, Keun-Hyeok
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Depth dependent modification of optical constants arising from H+ implantation in n-type 4H-SiC measured using coherent acoustic phonons

APL Photonics, 2016
Silicon carbide (SiC) is a promising material for new generation electronics including high power/high temperature devices and advanced optical applications such as room temperature spintronics and quantum computing.
Andrey Baydin, Halina Krzyzanowska, Munthala Dhanunjaya, S. V. S. Nageswara Rao, Jimmy L. Davidson, Leonard C. Feldman, Norman H. Tolk   +6 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Research on the In-Depth Interpretation of Measured Pressure Data During Fluid Sampling with Dual Packers

Cejing jishu
Dual packer is a kind of formation test pressure measurement sampling tool, the sampling process usually needs to be pumped for several hours or even more than ten hours to obtain formation fluid samples and pressure/flow rate data, but it can’t truly ...
YU Qiang, CHU Xiaodong, ZHOU Yanmin, QIN Xiaofei, KONG Sun, ZUO Youxiang   +5 more
doaj   +1 more source

Modelling the Spoon IRS diagnostic diagram

, 2009
We explore whether our models for starbursts, quiescent star-forming galaxies and for AGN dust tori are able to model the full range of IRS spectra measured with Spitzer.
Alexander, Andreas Efstathiou, Bruzual, Clements, Clements, Dale, Dopita, Dullemond, Dunne, Efstathiou, Efstathiou, Efstathiou, Efstathiou, Efstathiou, Farrah, Farrah, Granato, Hao, Hao, Hernan-Caballero, Hönig, Mathis, Michael Rowan-Robinson, Nenkova, Nenkova, Pier, Piovan, Rigopoulou, Roche, Rowan-Robinson, Rowan-Robinson, Rowan-Robinson, Rowan-Robinson, Rowan-Robinson, Rowan-Robinson, Rowan-Robinson, Rowan-Robinson, Rowan-Robinson, Ruiz, Schartmann, Siebenmorgen, Siebenmorgen, Siebenmorgen, Silva, Spoon, Takagi, Wang   +46 more
core   +2 more sources