Results 61 to 70 of about 11,557,043 (380)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Dynamic Measurement Error Modeling and Analysis in a Photoelectric Scanning Measurement Network

open access: yesApplied Sciences, 2018
A photoelectric scanning measurement network is a kind of distributed measurement system based on the principle of angle intersection, in which transmitters and photoelectric receivers are the main parts.
Shendong Shi   +6 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Differential‐sampling control algorithm and theoretical analysis for programmable‐Josephson‐voltage‐standard traceability application

open access: yesIET Science, Measurement & Technology
The programmable Josephson voltage standard (PJVS) provides a new way and higher accuracy for the traceability of traditional measurement standards.
Xiaodong Yin   +5 more
doaj   +1 more source

Covariate Measurement Error in Endogenous Stratified Samples [PDF]

open access: yes, 2004
In this paper we propose a general framework to deal with the presence of covariate mea-surement error in endogenous stratifield samples. Using Chesher’s (2000) methodology, we develop approximately consistent estimators for the parameters of the ...
Ramalho, Esmeralda
core  

Measurement Error in Lasso: Impact and Correction

open access: yes, 2014
Regression with the lasso penalty is a popular tool for performing dimension reduction when the number of covariates is large. In many applications of the lasso, like in genomics, covariates are subject to measurement error.
Frigessi, Arnoldo   +2 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Measurement Error Time-Correlation Modeling for Safety-Critical Navigation

open access: yesNavigation
In this paper, we develop and evaluate two new methods to derive high-integrity models of measurement error time correlation from experimental data. These models enable the determination of sequential estimation error variance bounds in safety-critical ...
Sandeep Jada, Mathieu Joerger
doaj   +1 more source

Universally Valid Error-Disturbance Relations in Continuous Measurements [PDF]

open access: yes, 2015
In quantum physics, measurement error and disturbance were first naively thought to be simply constrained by the Heisenberg uncertainty relation. Later, more rigorous analysis showed that the error and disturbance satisfy more subtle inequalities ...
Chen, Yanbei, Nishizawa, Atsushi
core   +1 more source

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