Results 61 to 70 of about 1,100,257 (311)
The programmable Josephson voltage standard (PJVS) provides a new way and higher accuracy for the traceability of traditional measurement standards.
Xiaodong Yin +5 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Time-varying coefficient models and measurement error [PDF]
This thesis is concerned with presenting and developing modeling approaches which allow for a time-varying effect of covariates by using time-varying coefficients. The different approaches are compared in simulation studies.
Breitner, S., Breitner, Susanne
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Error analysis of EXAFS measurements
We propose a method to analyze x-ray-absorption fine-structure data that avoids an arbitrary restriction of the size of the model-parameter space. It starts with an a priori guess of the model parameters which is introduced into the fitting procedure by Bayesian arguments. Two different descriptions are discussed to determine the relative impact of the
H J, Krappe, H H, Rossner
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Measurement Error Time-Correlation Modeling for Safety-Critical Navigation
In this paper, we develop and evaluate two new methods to derive high-integrity models of measurement error time correlation from experimental data. These models enable the determination of sequential estimation error variance bounds in safety-critical ...
Sandeep Jada, Mathieu Joerger
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Adjustment for Measurement Error
A variety of complications arise when imperfect measurements, W, are observed in place of a true variable of interest, X. In the context of linear and non-linear regression models where X is a covariate, regression parameter estimators obtained when W ...
Elliott, Laine E
core
A comparative analysis of vine leaves area measurement algorithms
More and more frequently in contemporary scientific literature information can be found on the use of mobile devices such as video cameras and smartphones by which an area of different objects, for example – vine leaves, can be measured.
Krasimira Georgieva +3 more
doaj

