Results 91 to 100 of about 2,105,065 (292)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Obesity and Health-Care Costs in Switzerland: Dealing with Endogeneity in Non-Linear Regression Models

open access: yesSwiss Journal of Economics and Statistics, 2016
Summary We draw microdata from the Swiss Household Panel to estimate the causal effect of obesity on the number of physician visits, the amount of hospital days, and the respective costs incurred.
Stefan Meyer
doaj   +1 more source

A method for calculating the effects of design errors and measurement errors on pump performance [PDF]

open access: yes, 1972
Technique has been developed for calculating effects of design errors and measurement errors on pump performance. Error equations and charts are utilized to relate amount of error in given performance parameter to amount of error in given design or ...
Anderson, D. A.
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

A calibration approach for compensating hysteresis and nonlinearity error in an MEMS based instrument for porewater pressure monitoring

open access: yesIET Science, Measurement & Technology
Micro‐electro‐mechanical system (MEMS) technology is becoming increasingly popular in geotechnical and hydrological monitoring due to their distinct features, including its small size, low cost, low energy consumption, and resistance to vibration shock ...
Milad Barzegar   +2 more
doaj   +1 more source

Portfolio Management: An investigation of the implications of measurement errors in stock prices on the creation, management and evaluation of stock portfolios, using stochastic simulations [PDF]

open access: yes
In this paper, we investigate the implications of measurement errors in the daily published stock prices on the creation and management of efficient portfolios.
Dikaios Tserkezos, Eleni Thanou Thanou
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Analysis of the Influence of Polarization Measurement Errors on the Parameter and Characteristics Measurement of the Fully Polarized Entomological Radar

open access: yesRemote Sensing
Measuring the orientation, mass and body length of migratory insects through entomological radar is crucial for early warnings of migratory pests.
Muyang Li   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Analysis of measurement errors for a superconducting phase qubit

open access: yes, 2006
We analyze several mechanisms leading to errors in a course of measurement of a superconducting flux-biased phase qubit. Insufficiently long measurement pulse may lead to nonadiabatic transitions between qubit states $|1>$ and $|0>$, before tunneling ...
Abraham G. Kofman   +9 more
core   +1 more source

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