Results 181 to 190 of about 2,105,065 (292)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Clustering Functional Data With Measurement Errors: A Simulation-Based Approach. [PDF]

Stat Med
Zhu T, Xue L, Tekwe C, Diaz K, Benden M, Zoh R.   +5 more
europepmc   +1 more source

Swept-source OCT reduces the risk of axial length measurement errors in eyes with cataract and epiretinal membranes. [PDF]

PLoS One, 2021
Faraldi F, Lavia CA, Nassisi M, Kilian RA, Bacherini D, Rizzo S.   +5 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Can measurement errors explain variance in the relationship between muscle- and tendon stiffness and range of motion?-a blinded reliability and objectivity study. [PDF]

Eur J Appl Physiol
Warneke K, Meder J, Plöschberger G, Oraže M, Zechner M, Jochum D, Siegel SD, Konrad A.   +7 more
europepmc   +1 more source

Sensitivity Analysis of Determining the Material Parameters of an Asphalt Pavement to Measurement Errors in Backcalculations. [PDF]

Materials (Basel), 2021
Tutka P, Nagórski R, Złotowska M, Rudnicki M.   +3 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

TMBocelot: an omnibus statistical control model optimizing the TMB thresholds with systematic measurement errors. [PDF]

Front Immunol
Lai X, Wang S, Zhang X, Zhu X, Liu Y, Chang Z, Wang X, Shao Y, Wang J, Wang Y.   +9 more
europepmc   +1 more source

Statistical inferences for single-index models with measurement errors. [PDF]

J Appl Stat, 2021
Huang Z, Lou W.
europepmc   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source