Results 121 to 130 of about 23,344,103 (371)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Construction noise database (phase 3): Evaluation of established measurement protocol [PDF]
Executive Summary 1.1 The established method for obtaining noise emission data for the update of a database of noise from construction plant is examined. 1.2 The established measurement protocol involves the collection of plant noise measurements using
Moorhouse, AT, Waddington, DC
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Background While highlighting is one of the most common strategies to enhance reading comprehension, little is known about how highlighting behavior and its relationship with performance varies across cultures.
Ella Anghel, Matthias von Davier
doaj +1 more source
Originally developed as an effective feature selection method in healthcare predictive analytics, Recursive Feature Elimination (RFE) has gained increasing popularity in Educational Data Mining (EDM) due to its ability to handle high-dimensional data and
Okan Bulut +3 more
doaj +1 more source
Evaluating the Quality of Ground-Based Microwave Radiometer Measurements and Retrievals Using Detrended Fluctuation and Spectral Analysis Methods [PDF]
K. Ivanova +5 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Advanced evaluation of vacuum UV detector- spectroscopy systems for capsule reentry measurements [PDF]
Vacuum ultraviolet detector evaluation - spectroscopy systems for capsule reentry ...
Betz, H. T. +2 more
core +1 more source
Lithium Sulphur Batteries [PDF]
S+C cathode material was prepared by simple solid-state reaction in ball mill. Content of sulphur was approximately 80 wt. % in final sample. Cyclic voltammetry and galvanostatic charge/discharge techniques were used for characterization of the samples ...
Juračka, M.
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

