Results 161 to 170 of about 23,344,103 (371)

Control of blood pressure as measured at home and office, and comparison with physicians' assessment of control among treated hypertensive patients in Japan: First Report of the Japan Home versus Office Blood Pressure Measurement Evaluation (J-HOME) study.

Hypertension Research, 2004
T. Ohkubo, T. Obara, J. Funahashi, M. Kikuya, K. Asayama, H. Metoki, Takuya Oikawa, Hisaki Takahashi, J. Hashimoto, K. Totsune, Y. Imai   +10 more
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

GRDL: A New Global Reservoir Area‐Storage‐Depth Data Set Derived Through Deep Learning‐Based Bathymetry Reconstruction

Water Resources Research
Reservoirs play a critical role in the global water cycle by regulating the flow of water from the environment into human systems. Accurate estimation of the area‐storage‐depth relationships for global reservoirs is essential for effective hydrological ...
Zhen Hao, Fang Chen, Xiaofeng Jia, Xiaobin Cai, Chao Yang, Yun Du, Feng Ling   +6 more
doaj   +1 more source

Deep learning-based automatic blood pressure measurement: evaluation of the effect of deep breathing, talking and arm movement. [PDF]

Ann Med, 2019
Pan F, He P, Chen F, Pu X, Zhao Q, Zheng D.   +5 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Evaluation of Hydrogen Enbrittlement by Slow Speed SZW Measurement Method

, 2000
Hiroyuki Masuda, Saburo MATSUOKA
openalex   +2 more sources

Study on measurement of internal anal sphincter movement in dogs (application as evaluation method on defecation disorder)-2^nd report

, 2020
Kazuaki Sasaki, Masakazu Imaizumi, Seiiti Katayama, Keiko Harada, Katsuhide Nishi   +4 more
openalex   +2 more sources

Adaptation and evaluation of the measurement properties of the Brazilian version of the Self-efficacy for Appropriate Medication Adherence Scale [PDF]

, 2016
Rafaela Batista dos Santos Pedrosa, Roberta Cunha Matheus Rodrigues   +1 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source