Results 111 to 120 of about 8,819,646 (297)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Measuring and monitoring skeletal muscle function in COPD: current perspectives
International Journal of COPD, 2019 Sarah Marklund,1 Kim-Ly Bui,2 Andre Nyberg11Department of Community Medicine and Rehabilitation, Section of Physiotherapy, Umeå University, Umeå, Sweden; 2Rehabilitation Department, Faculty of Medicine Laval University and Centre de recherche,
Marklund S, Bui KL, Nyberg A
doaj
Blood rheological properties and methods of their measurement
Annales Academiae Medicae SilesiensisFrom the physical point of view, blood is a multi-phase and multi-component system; plasma is the dispersion medium and the morphotic elements are the dispersed phase.
Tomasz Pryzwan +3 more
doaj +1 more source
Evaluation of the Uncertainty of Edge Detector Algorithms [PDF]
, 2006 This paper deals with the analytical expression of the uncertainty on edge localization in image analysis applications. The analysis carried out relates analytically the uncertainty affecting the intensity of the input image to the output uncertainty of ...
PAOLILLO, Alfredo +2 more
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Low-Coherence Interferometry for Measurement of Properties of Optical Components
, 2010 We present a modification of the interferometric method for the measurement of refractive index or thickness of optical devices using an easily aligned, almost all-fiber Michelson interferometer.
Norbert Tarjanyi +2 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
A multi-utility smart metering architecture to improve energy efficiency
, 2015 Smart meters are essential tools to increase energy efficiency of buildings and grid. However, to get a real benefit from them, an effective integration between the different energy domestic metering devices and display, as well as a suitable post ...
Betta, G. +10 more
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source