Results 141 to 150 of about 822,595 (263)

A peer victimisation scale based on a behavioural consequences measurement strategy. [PDF]

Singapore Med J, 2016
Han J, Xia J, He Q, Shao Y, Zhan Y, Liu G, Wang X.   +6 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Patient-Relevant Measurement Strategy to Assess Clinical Benefit of Novel Therapies for Non-metastatic Cutaneous Squamous Cell Carcinoma. [PDF]

Oncol Ther
Rofail D, Ciesluk A, Lovell T, Marquis P, Fury MG, Chen CI.   +5 more
europepmc   +1 more source

A new soft tissue volume measurement strategy using ultrasonography. [PDF]

Lymphat Res Biol, 2014
Hwang JH, Lee CH, Lee HH, Kim SY.
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Instrumentation and Measurement Strategy for the NOAA SENEX Aircraft Campaign as Part of the Southeast Atmosphere Study 2013. [PDF]

Atmos Meas Tech, 2016
Warneke C, Trainer M, de Gouw JA, Parrish DD, Fahey DW, Ravishankara AR, Middlebrook AM, Brock CA, Roberts JM, Brown SS, Neuman JA, Lerner BM, Lack D, Law D, Hübler G, Pollack I, Sjostedt S, Ryerson TB, Gilman JB, Liao J, Holloway J, Peischl J, Nowak JB, Aikin K, Min KE, Washenfelder RA, Graus MG, Richardson M, Markovic MZ, Wagner NL, Wagner NL, Welti A, Veres PR, Edwards P, Schwarz JP, Gordon T, Dube WP, McKeen S, Brioude J, Ahmadov R, Bougiatioti A, Lin JJ, Nenes A, Wolfe GM, Hanisco TF, Lee BH, Lopez-Hilfiker FD, Thornton JA, Keutsch FN, Kaiser J, Mao J, Hatch C.   +51 more
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Measurement strategy and statistical power in studies assessing gait stability and variability in older adults. [PDF]

Aging Clin Exp Res, 2016
Toebes MJ, Hoozemans MJ, Mathiassen SE, Dekker J, van Dieën JH.   +4 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source