Results 191 to 200 of about 822,595 (263)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Digital health literacy of adolescents: A scoping review protocol. [PDF]

PLoS One
Linney H, van Someren K, Keogh S.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Healthcare Quality Systems: International Frameworks, Evaluation and Improvement Strategies. [PDF]

Healthcare (Basel)
Ntais C, Talias MA.
europepmc   +1 more source

A High-Precision Screen-Printed Glucose Sensor with In Situ Impedance-Based HCT Correction and Temperature Compensation. [PDF]

Biosensors (Basel)
Lu M, Cheng J, Lei Q, Guo J, Chen K.
europepmc   +1 more source

Measuring multisector nutrition and health intervention coverage using composite coverage analysis methods: a scoping review and methodological guidance. [PDF]

BMJ Open
Morrison T, Akseer N, Heidkamp R, Maïga A, Tasic H.   +4 more
europepmc   +1 more source

Cooperative Design of Ranging and Communication for In-Band Full-Duplex Inter-Satellite Links. [PDF]

Sensors (Basel)
Feng H, Yang Z, Ma H, Jiao Y, Wu T, Cai Y, Ma H, Shan Z.   +7 more
europepmc   +1 more source

Formation-Constrained Cooperative Localization for UAV Swarms in GNSS-Denied Environments. [PDF]

Sensors (Basel)
Li Q, Wang P, Li X, Zhang J, Luo Y, Yu W, Cheng H.   +6 more
europepmc   +1 more source