Results 61 to 70 of about 7,033,580 (327)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Assessing the measurement uncertainty of qualitative analysis in the clinical laboratory
Journal of Laboratory Medicine, 2020 Measurement uncertainty is a parameter that is associated with the dispersion of measurements. Assessment of the measurement uncertainty is recommended in qualitative analyses in clinical laboratories; however, the measurement uncertainty of qualitative ...
Lim Yong Kwan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Practical Laboratory Medicine, 2018 Procedures for assessing the uncertainty in measurement and estimates of biological variation are currently available for many measurands capable of direct analytical measurement.
Ian Farrance +2 more
doaj +1 more source
Speckle: International Conference on Speckle Metrology, 2018 This communication presents a set of expressions to evaluate the standard uncertainty and covariance of the real an imaginary parts of the complex-valued field resulting from the reconstruction of digital holograms by using the Fresnel approximation ...
Á. Doval +3 more
semanticscholar +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Enhanced Vectorial Measurement Uncertainty Model
MetrologyQuantitative determination of the uncertainty of a measurement result is the key to assessing the quality and reliability of a measurement process and its result.
Ingo Ortlepp +9 more
doaj +1 more source
Developing and validating of the Clinical Uncertainty Measurement Questionnaire (CUMQ) among practicing physicians and clinical residents in Iran [PDF]
, 2022 Shirin Ghanavati +3 more
openalex +1 more source
Determination of measurement uncertainty by Monte Carlo simulation [PDF]
Series on Advances in Mathematics for Applied Sciences, 2017 Modern coordinate measurement machines (CMM) are universal tools to measure geometric features of complex three-dimensional workpieces. To use them as reliable means of quality control, the suitability of the device for the specific measurement task has ...
D. Heißelmann +5 more
semanticscholar +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source