Results 211 to 220 of about 5,211,328 (291)

Conventional Versus Virtual Reality-Based Hess-Lancaster Assessment: Agreement and Repeatability in Ocular Motility Evaluation. [PDF]

J Eye Mov Res
Povedano-Montero FJ, Perales-Serrano Á, León Lobo D, González-Jiménez R, Bernárdez-Vilaboa R, Cedrún-Sánchez JE.   +5 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Supine and Sitting Intraocular Pressure Measurements Using iCare HOME2 Self-Tonometry and iCare IC200 Rebound Tonometry in Japanese Open-Angle Glaucoma Patients. [PDF]

Clin Ophthalmol
Nakamura S, Hollό G, Fukuda Y, Ishida T, Kita Y.   +4 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Multi-sensor microclimate and tree canopy dataset from a linden tree for green infrastructure validation. [PDF]

Sci Data
Schöneberger P, Sinsel T, Simon H, Bruse M.   +3 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Clinical Reliability of AI-Based Cephalometric Analysis Using WebCeph: A Comparative Agreement Study. [PDF]

J Clin Med
Azari-Mehr A, Bisbal-Puchades A, Marqués-Martínez L, Carmona-Santamaria M, García-Miralles E, Aura-Tormos JI, Guinot-Barona C.   +6 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Oscillometric blood pressure values in infants at 3, 6 and 12 months of age: a cohort study. [PDF]

BMJ Paediatr Open
Ørbeck Vallevik E, Holten-Andersen MN, Lødrup Carlsen KC, Skjerven HO, Vettukattil R, Rueegg CS, Rehbinder EM, Nordlund B, Söderhäll C, Hedlin G, Haugen GN, Staff AC, Nilsen M, Holmstrøm H.   +13 more
europepmc   +1 more source