Results 101 to 110 of about 5,473,656 (314)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Improve the performance of cold crucible used for emissivity measurement of molten metal

Case Studies in Thermal Engineering
High-purity titanium (Ti) and its alloys are among the most promising materials for advanced turbine blades in aerospace engines. Electromagnetic cold crucible melting is a novel technique for producing contamination-free pure Ti ingots.
Gangquan Wang, Yinxue Bai, Baolin Zhao, Longfei Li, Yue Liu, Kaihua Zhang, Yufang Liu, Kun Yu   +7 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Optimization of Risk Measures [PDF]

We consider optimization problems involving coherent risk measures. We derive necessary and sufficient conditions of optimality for these problems, and we discuss the nature of the nonanticipativity constraints.
Andrzej Ruszczynski, Alexander Shapiro
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Comonotonic Measures of Multivariate Risks. [PDF]

We propose a multivariate extension of a well-known characterization by S. Kusuoka of regular and coherent risk measures as maximal correlation functionals.
Henry, Marc, Galichon, Alfred, Ekeland, Ivar   +2 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Validation of 4TP Impedance Bridge Developed at GUM

Energies
Impedance methods are gaining importance each year and have recently become an essential tool for diagnosing batteries, capacitors, and fuel cells.
Marian Kampik, Krzysztof Musioł, Adam Ziółek, Jolanta Jursza, Maciej Koszarny   +4 more
doaj   +1 more source

Provisional Measures Issued by ICSID Tribunals

, 2018
Analysis of the legal framework and the arbitral practice surrounding provisional measures issued by ICSID arbitral tribunals, in comparison with other international courts and ...
Domenico Pauciulo
core  

Measurable sets of measures [PDF]

Pacific Journal of Mathematics, 1964
Dubins, Lester, Freedman, David
openaire   +3 more sources