Results 191 to 200 of about 5,473,656 (314)

Patient safety measures for virtual consultations in primary care: a systematic review. [PDF]

BMJ Qual Saf
Lunova T, Hurndall KH, Kirk UB, Franklin BD, Darzi A, Neves AL.   +5 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Agreement and Reliability of Running Stride-Time Variability Analyses from Wearable Devices. [PDF]

Sensors (Basel)
Jones BDM, Wheat J, Middleton K, Carey DL, Heller B.   +4 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A Simple and Fast Colorimetric Assay for the Detection of Chloride Ions Based on Etching of Silver Triangular Nanoplates

ACS Omega
Ning Feng, Xiaodie Han, Anran Wang, Lixia LI, Yufang Liu   +4 more
doaj   +1 more source

Effects of extra training with active cycle of breathing technique relative to whole-body breathing exercise in older adults with stable COPD. [PDF]

PLoS One
Lai H, Chen L, Chan RW, Pan Q, Chen Q, Chen Y, Xie Z.   +6 more
europepmc   +1 more source

A family of accessibility measures derived from spatial interaction principles

Transportation planning has long prioritized the efficiency of movement, or mobility. However, the concept of accessibility represents a more comprehensive evolution, shifting focus from mere movement to the potential to reach (i.e., spatially interact ...
Christopher D. Higgins, Rafael H. M. Pereira, Anastasia Soukhov, Antonio Paez   +3 more
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Correction: Caring is not always sharing: A scoping review exploring how COVID-19 containment measures have impacted unpaid care work and mental health among women and men in Europe. [PDF]

PLoS One
Gencer H, Brunnett R, Staiger T, Tezcan-Güntekin H, Pöge K.   +4 more
europepmc   +1 more source