Results 101 to 110 of about 6,994 (188)

Chemogenetic control of GABAergic neurons within the interpeduncular nucleus reveals dissociable behavioral components of the nicotine withdrawal phenotype

Neurobiology of Disease
Chronic exposure to nicotine results in the development of a dependent state such that a withdrawal syndrome is elicited upon cessation of nicotine. The interpeduncular nucleus (IPN) contains a high concentration of nicotinic acetylcholine receptors ...
Anabel M.M. Miguelez Fernández, Shana Netherton, Seshadri B. Niladhuri, Alexander C. Brown, Patricia Rivera, Kuei Y. Tseng, Christian J. Peters   +6 more
doaj   +1 more source

Novel agonist of α4β2* neuronal nicotinic receptor with antinociceptive efficacy in rodent models of acute and chronic pain

Journal of Pain Research, 2018
Roberto T Sudo,1,2 Kenichiro Hayashida,3 Aluizio N Santos,2 Masahito Kawatani,3 Carlos ES Monteiro1 Roberto D Moreira,4 Margarete M Trachez,1 Guilherme C Montes,1 Gisele Zapata-Sudo1 1Program of Research in Drug Development of Biomedical Science ...
Sudo RT, Hayashida K, Santos AN, Kawatani M, Monteiro CES, Moreira RD, Trachez MM, Montes GC, Zapata-Sudo G   +8 more
doaj  

MECAMYLAMINE [PDF]

Anesthesiology, 1959
openaire   +1 more source

Cholinergic regulation on polymeric immunoglobulin receptor expression in Caco-2 cells

Acta Pharmaceutica
The polymeric immunoglobulin receptor (pIgR) mediates trans cytosis of IgA, a pivotal anti-inflammatory player of the mucosal immune system. Transcytosis mediated by pIgR entails protein effectors of vesicle-mediated transport involved in signal pathway ...
Higuera-Martínez German, Levaro-Loquio David, Reséndiz-Albor Aldo Arturo, Martínez Ivonne Maciel Arciniega, Guevara-Rubio Munich, Drago-Serrano Maria Elisa, Pacheco-Yepez Judith   +6 more
doaj   +1 more source

Synthesis of mecamylamine analogues

, 2010
This project was concerned with the synthesis of structural analogues of the neuronal nicotinic acetylcholine receptor (nAChR) antagonist mecamylamine (MA). MA was used clinically as an antihypertensive compound since the 1950s but has more recently been investigated for its therapeutic potential as an anti-addictive and antidepressant compound ...
openaire   +1 more source

The neurochemical basis of photic entrainment of the circadian pacemaker [PDF]

Circadian rhythmicity in mammals is controlled by the action of a light-entrainable hypothalamus, in association with two cell clusters known as the supra chiasmatic nuclei (SCN).
Buckley, Becky, Lutton, Lewis M., Rea, Michael A.   +2 more
core   +1 more source

Paired associates learning performance in rats requires the nucleus reuniens. [PDF]

Behav Neurosci
Besosa C, Baksh A, Braden R, Tomczak S, Lovett S, Maurer AP, Burke SN.   +6 more
europepmc   +1 more source

Synchronous activation of striatal cholinergic interneurons induces local serotonin release. [PDF]

Nat Commun
Matityahu L, Hobel ZB, Berkowitz N, Malgady JM, Gilin N, Plotkin JL, Goldberg JA.   +6 more
europepmc   +1 more source

Optimizing a <i>C. elegans</i> whole organism screen biased for chemicals that target the nematode clade specific receptor EAT-2. [PDF]

MicroPubl Biol
Nvenankeng HA, Goodchild J, Harlow P, O'Connor V, Holden-Dye L.   +4 more
europepmc   +1 more source

Treatment of Hypertension with Pentolinium and Mecamylamine [PDF]

BMJ, 1959
H T, SEARS, P J, SNOW, I B, HOUSTON
openaire   +2 more sources