Results 141 to 150 of about 6,994 (188)

From Airways to Alveoli: A Review of Smoking-Related Respiratory Disorders. [PDF]

Cureus
Rudwan AH, Al Adhreai E, Ali HE, Albaik S, Allo Y, Osman R, Bakhiet Y, Rudwan A.   +7 more
europepmc   +1 more source

VNS improves VSMC metabolism and arteriogenesis in infarcted hearts through m/n-AChR-Akt-SDF-1α in adult male rats. [PDF]

J Mol Histol
Li XY, Liu JQ, Wang Y, Chen Y, Hu WH, Lv YX, Wu Y, Lv J, Tang JM, Kong D.   +9 more
europepmc   +1 more source

Neonicotinoid Pesticides Affect Developing Neurons in Experimental Mouse Models and in Human Induced Pluripotent Stem Cell (iPSC)-Derived Neural Cultures and Organoids. [PDF]

Cells
Mariani A, Comolli D, Fanelli R, Forloni G, De Paola M.   +4 more
europepmc   +1 more source

Cholinergic Control of GnRH Neuron Physiology and Luteinizing Hormone Secretion in Male Mice: Involvement of ACh/GABA Cotransmission. [PDF]

J Neurosci
Vastagh C, Farkas I, Csillag V, Watanabe M, Kalló I, Liposits Z.   +5 more
europepmc   +1 more source

The influence of CHRNA5 and D398N missense variation on social and emotional behaviors in rodents and humans. [PDF]

Transl Psychiatry
de Chaumont F, Icick R, Gorwood P, Granon S, Forget B, Bouarab C, Mattioni J, Bourgeron T, Maskos U, Ramoz N, Besson M.   +10 more
europepmc   +1 more source

Glucagon-Like-Peptide-2 Stimulates Lacteal Contractility and Enhances Chylomicron Transport in the Presence of an Intact Enteric Nervous System. [PDF]

Gastro Hep Adv
Syed-Abdul MM, Tian L, Samuel T, Wong A, Hong YK, Dacosta RS, Lewis GF.   +6 more
europepmc   +1 more source

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Nicotine-mecamylamine interactions

Clinical Pharmacology & Therapeutics, 1999
Mecamylamine blocks nicotinic cholinergic receptors and has been proposed, in combination with nicotine, as a novel therapy to aid smoking cessation. The objective of this study was to characterize the pharmacokinetic and pharmacodynamic interactions between transdermal mecamylamine and intravenous nicotine.Twelve cigarette smokers were studied while ...
S, Zevin, P, Jacob, N L, Benowitz
openaire   +2 more sources

Psychosis, Possibly Induced by Mecamylamine

New England Journal of Medicine, 1957
MECAMYLAMINE∥ is a ganglionic-blocking agent, recommended for the reduction of elevated blood pressure. In contrast to previously available ganglionic-blocking agents, it is well absorbed when taken by mouth. This advantage has led to the hope that it might be easier and safer to use than other ganglionic-blocking agents because of the lessened risk of
Q B, DEMING, M E, HODES, J G, EDREIRA, A, BALTAZAR   +3 more
openaire   +2 more sources

Mecamylamine (Targacept).

IDrugs : the investigational drugs journal, 2006
Targacept Inc, under license from the University of South Florida, is developing a low-dose, liquid gel capsule formulation of the nicotinic acetylcholine antagonist mecamylamine, as a potential treatment for various neuropsychiatric disorders.
Abhay, Singh, Deepak K, Das, Michael E, Kelley   +2 more
openaire   +1 more source

Hypotensive amines: unbridged cyclohexane analogues of mecamylamine

Journal of the Chemical Society C: Organic, 1970
Some polyalkylcyclohexylamines related to pempidine have been prepared as potential ganglion-blocking agents, and their methylation has been examined. An N-formyl derivative, prepared via the Ritter reaction, showed anomalous behaviour on hydrolysis. No useful pharmacological activity was found.
E, Lunt, R, Wragg
openaire   +2 more sources