Results 151 to 160 of about 6,994 (188)

Mecamylamine and Ethanol Preference in Healthy Volunteers

Alcoholism: Clinical & Experimental Research, 2005
Recent evidence suggests that some of the behavioral effects of alcohol may be mediated through actions on nicotinic acetylcholine receptors. Mecamylamine, a nicotinic acetylcholine receptor antagonist, reduces alcohol preference and consumption in alcohol-preferring rats, and in humans, mecamylamine dampens some of the subjective, or mood-altering ...
Elizabeth M, Young, Stephen, Mahler, Henry, Chi, Harriet, de Wit   +3 more
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MECAMYLAMINE (INVERSINE) IN THE TREATMENT OF HYPERTENSION

Journal of the American Medical Association, 1957
• The effectiveness of combining reserpine with mecamylamine in treating hypertension was tested in 75 patients, all of whom had sustained blood pressure levels above 150/100 mm. Hg before treatment. A comparison was made between one group of 17 patients receiving mecamylamine alone and another group of 58 receiving mecamylamine with reserpine.
J, MOYER, C, HEIDER, E, DENNIS
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Mecamylamine attenuates ephedrine-induced hyperactivity in rats

Pharmacology Biochemistry and Behavior, 2005
Ephedrine is a central nervous system stimulant that has a pharmacological profile similar to amphetamines. Ephedrine induces hyperactivity after acute administration to rats and locomotor sensitization develops to ephedrine with repeated administration.
Dennis K, Miller, Ines L, Segert
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Renal Elimination of 3-Methylaminoisocamphane Hydrochloride (Mecamylamine)

American Journal of Physiology-Legacy Content, 1956
Mecamylamine, 3-methylaminoisocamphane hydrochloride, a secondary amine with a pka of 11.4, can be both actively secreted and actively reabsorbed by the renal tubules in the dog. Net secretion occurs when the urine is acid; net reabsorption occurs when the urine is alkaline.
J E, BAER, K H, BEYER, S F, PAULSON, H F, RUSSO   +3 more
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Drug Therapy (Mecamylamine) of Hypertension

A.M.A. Archives of Internal Medicine, 1956
Ganglionic blocking agents appear to be the most potent therapeutic agents for reducing the blood pressure in patients with severe hypertension. However, the orthostatic effect and the variability in blood pressure response to currently available ganglionic blocking agents are the most serious limiting factors in the use of these agents and may ...
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[3H]mecamylamine binding to rat brain membranes. Studies with mecamylamine and nicotine analogues.

Biochemical pharmacology, 1990
Mecamylamine, an antagonist to nicotine, does not compete at the nicotinic recognition site, but is believed to block the ion channel of the nicotinic receptor. The present study demonstrates specific, saturable [3H]mecamylamine binding in rat brain membranes. [3H]Mecamylamine binding was destroyed by heating at 100 degrees and trypsin.
S, Banerjee, J S, Punzi, K, Kreilick, L G, Abood   +3 more
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Mecamylamine, a New, Orally Effective,

A.M.A. Archives of Internal Medicine, 1956
Stone and his co-workers * have reported recently on certain unusual pharmacological properties of mecamylamine (3-methylaminoisocamphane) hydrochloride. This compound, a secondary amine, produces a marked and prolonged degree of blood pressure reduction and ganglionic blockade in animals.
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PHARMACOLOGY OF MECAMYLAMINE

The American Journal of the Medical Sciences, 1956
R V, FORD, J C, MADISON, J H, MOYER
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Mecamylamine

2010
Michael M. Morgan, MacDonald J. Christie, Thomas Steckler, Ben J. Harrison, Christos Pantelis, Christof Baltes, Thomas Mueggler, Markus Rudin, Lawrence H. Price, Malcolm Lader, R. H. Belmaker, Joseph H. Friedman, Peter Verhaert, Per Svenningsson, Per E. Andrén, Giovanni Hernandez, Peter Shizgal, Bart Ellenbroek, Trevor W. Robbins, Peter Verhaert, Per Svenningsson, Per E. Andrén, Paul Newhouse, Heather Wilkins, Lance R. McMahon, Luis Stinus, Stéphanie Caillé, Martine Cador, Mary E. Cain, Michael T. Bardo, Sarah Morgan, Angus Mackay, Lucio Tremolizzo, Gessica Sala, Carlo Ferrarese, Alfonso Abizaid, Shimon Amir, Alfonso Abizaid, Shimon Amir, Stephen M. Stahl, Meghan M. Grady, Theodora Duka, Rodrigo Andrade, Yesne Alici, William Breitbart, Debby Van Dam, Peter Paul De Deyn, Warren H. Meck, Catalin V. Buhusi, Malcolm Lader, Martine Cador, Marie-Louise G. Wadenberg, Tomek J. Banasikowski, Richard J. Beninger, Stefan Leucht, Kim Wolff, Peter Verhaert, Per Svenningsson, Per E. Andrén, Elizabeth C. Warburton, Anne M. Andrews, Greg A. Gerhardt, Lynette C. Daws, Johannes Mosbacher, Gabriele Fischer, Annemarie Unger, Martine Cador, Ian P. Stolerman, Seiya Miyamoto, Iain S. McGregor, Murray R. Thompson, Paul D. Callaghan, Trevor W. Robbins, Nachum Dafny, Bernard Le Foll, Theodora Duka, Albert Adell, Francesc Artigas, Anne M. Andrews, Greg A. Gerhardt, Lynette C. Daws, Roberto William Invernizzi, Ennio Esposito, Jelena Nesic, Theodora Duka, Yesne Alici, William Breitbart, Josef Marksteiner, Irene Adelt, Huaiyu Yang, George I. Papakostas, Malcolm Lader, Klaus A. Miczek, R. Hamish McAllister-Williams, Tomasz Schneider, Stephen B. Dunnett, Andrew Young, Klaus A. Miczek, Michael Minzenberg, W. Wolfgang Fleischhacker, Andrew Holt, Darrell D. Mousseau, Glen B. Baker, Stephen M. Stahl, Meghan M. Grady, Andreas Marneros, Guy M. Goodwin, Seiya Miyamoto, Mohammed Shoaib, Mitul A. Mehta, Seiya Miyamoto, Stephen C. Fowler, Joachim Liepert, Thomas R. E. Barnes, Christof Baltes, Thomas Mueggler, Markus Rudin, Ennio Esposito, Roberto William Invernizzi, Josee E. Leysen, Ben J. Harrison, Christos Pantelis, Ronald F. Mucha, Holden D. Brown, Michael E. Ragozzino, Michael E. Ragozzino, Holden D. Brown, Paul Newhouse, Heather Wilkins, R. Andrew Chambers   +129 more
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Mecamylamine

2007
S.J. Enna, David B. Bylund
openaire   +1 more source