Results 131 to 140 of about 1,527 (247)

Mechanisms of opening of aortic valve

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 1980
openaire   +2 more sources

Pediatric Developmental Safety Assessment: Are We Ready for the Next Thalidomide?

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pediatric drug development has achieved remarkable success in the last 20 years with over 1,000 products studied in pediatric patients. This success has been driven in part by an increased understanding of pediatric disease processes. The aspect that has been largely overlooked is the potential adverse effect of new drugs on pediatric developmental ...
Gilbert J. Burckart   +6 more
wiley   +1 more source

The role of the Prognostic Nutritional Index in predicting survival and rehospitalization after surgical aortic valve replacement. [PDF]

open access: yesIndian J Thorac Cardiovasc Surg
D'Alonzo M   +6 more
europepmc   +1 more source

Permeability of granite from a shallow buried mountain pipe gallery tunnel under unloading confining pressure

open access: yesDeep Underground Science and Engineering, EarlyView.
Triaxial compression tests under unloading confining pressure conditions were conducted to systematically analyze the permeability behavior of granite retrieved from the different classification surrounding rocks. Abstract The rock mass within mountain tunnels undergoes complex changes in permeability, strength, and deformation during tunneling ...
Xiaoyan Zhang   +4 more
wiley   +1 more source

Multi‐factor coupling effects in hydraulic fracturing of laminated shale: Experimental insights and physics‐informed neural network‐driven optimization

open access: yesDeep Underground Science and Engineering, EarlyView.
This study establishes a multi‐factor coupling framework for predicting breakdown pressure in laminated shale by integrating experimental hydraulic fracturing tests, physics‐informed neural networks (PINNs), and Sobol sensitivity analysis. It reveals how differential stress, the bedding dip angle, and the injection rate interact to influence fracture ...
Tao Wang   +6 more
wiley   +1 more source

Investigation on the mechanical behavior of the multiple‐layered lining structure of a water conveyance tunnel with high internal water pressure

open access: yesDeep Underground Science and Engineering, EarlyView.
This study presents large‐scale similarity model testing (geometric ratio 3.6) of an innovative multiple‐layered lining system—comprising exterior precast segments, middle self‐compacting concrete, and an interior steel pipe—for high‐pressure (0.75 MPa) water conveyance tunnels.
Ramin Asadi   +4 more
wiley   +1 more source

Role of SoxE transcription factors in development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

In Silico and In Vitro Comparison of Seven Closed and Semi-Closed Leaflet Designs for Transcatheter Heart Valve Replacements. [PDF]

open access: yesBioengineering (Basel)
Breitenstein-Attach A   +8 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy