Results 131 to 140 of about 3,550,619 (297)

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

5. On the Oxidation of Phenyl Alcohol, and a Mechanical Arrangement adapted to illustrate Structure in the Nonsaturated Hydrocarbons [PDF]

John Dewar
openalex   +1 more source

VII.--THE MECHANICAL TREATMENT OF FRACTURES UNDER WAR CONDITIONS [PDF]

, 1916
R. Jones
openalex   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Pluralistic Mechanism

THEORIA. An International Journal for Theory, History and Foundations of Science, 2017
An argument recently proposed by Chirimuuta (2014) seems to motivate the rejection of the claims that every neurocognitive phenomenon can have a mechanistic explanation and that every neurocognitive explanation is mechanistic. In this paper, I focus on efficient coding models involving the so-called “canonical neural computations” and argue that ...
openaire   +4 more sources

Study on the Effect of Jute CNFs Addition on the Water Absorption and Mechanical Properties of Geopolymer Concrete

Buildings
This study investigates the influence of thermoplastic polyurethane (TPU) reinforced with jute cellulose nanofibers (CNFs) on the water absorption and mechanical properties of geopolymer concrete.
Siti Syazwani Nordin, Ervina Efzan Mhd Noor, Nurhidayatullaili Muhd Julkapli, Aeslina Abdul Kadir   +3 more
doaj   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

First-Principles Investigation of Diverse Properties of X₂CaTa₂O₇ (X = Li, Na, K, and Rb) Ruddlesden–Popper Compounds for Photovoltaic Applications

Crystals
For the first time, we explored the optical, electronic, mechanical, and structural properties of the Ruddlesden–Popper phase family member X2CaTa2O7 (X = Li, Na, K, and Rb) by using density functional theory (DFT) with the Perdew–Burke–Ernzerhof (PBE ...
Ahmad Hussain, Nawishta Jabeen, Ali Yaqoob, Sumaira Zafar, Muhammad Usman Khan, Eman A. Ayob, Mohamed E. Khalifa   +6 more
doaj   +1 more source

2. On a Universal Tendency in Nature to the Dissipation of Mechanical Energy. [PDF]

William Thomson
openalex   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source