Results 91 to 100 of about 1,395,295 (247)

Accelerated Search for BaTiO3‐Based Ceramics with Large Energy Storage at Low Fields Using Machine Learning and Experimental Design

open access: yesAdvanced Science, 2019
The problem that is considered is that of maximizing the energy storage density of Pb‐free BaTiO3‐based dielectrics at low electric fields. It is demonstrated that how varying the size of the combinatorial search space influences the efficiency of ...
Ruihao Yuan   +7 more
doaj   +1 more source

A review of mechanical seals tribology and condition monitoring [PDF]

open access: yes, 2013
Mechanical seals have become one of the most popular sealing systems for rotating machinery because of low leakage and absence of a requirement for routine maintenance.
Ball, Andrew   +2 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Low-cycle fatigue testing methods [PDF]

open access: yes
The good design of highly stressed mechanical components requires accurate knowledge of the service behavior of materials. The main methods for solving the problems of designers are: determination of the mechanical properties of the material after cyclic
Lieurade, H. P.
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Research progress in repair and remanufacture of compressor blisk

open access: yesJournal of Aeronautical Materials
The application of compressor blisk is one of the typical technologies of high-performance engines. However,due to its contact with high-speed airflow containing various solids,a variety of different forms of structural damage and performance degradation
ZHANG Gao   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The mechanical behavior of shales [PDF]

open access: yes, 2019
The thesis comprises three experimental studies, which were carried out to unravel the short- as well as the long-term mechanical properties of shale rocks. Short-term mechanical properties such as compressive strength and Young’s modulus were taken from recorded stress-strain curves of constant strain rate tests.
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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