Results 61 to 70 of about 1,395,295 (247)

Strong yet superelastic ceramic aerogel enabled by synergistic soft-hard inter-nanowire nodes

Nature Communications
Elastic ceramic aerogels have drawn broad attention for use in aerospace, energy storage, and thermal protection systems, where lightweight structures with thermal stability and mechanical robustness are required. Yet their practical application is often
De Lu, Lei Su, Lei Zhuang, Min Niu, Kang Peng, Pengcheng Zhang, Xiaowu Wang, Zhentao Ni, Shuhai Jia, Hongjie Wang   +9 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Detecting deformation mechanisms of metals from acoustic emission signals through knowledge-driven unsupervised learning

Nature Communications
Timely detection of deformation mechanisms in metallic structural materials is essential for early-warning alerts on potential damages and fractures.
Boyuan Gou, Yan Chen, Songhua Xu, Jun Sun, Turab Lookman, Ekhard K. H. Salje, Xiangdong Ding   +6 more
doaj   +1 more source

Probing the mechanical properties of graphene using a corrugated elastic substrate

, 2010
The exceptional mechanical properties of graphene have made it attractive for nano-mechanical devices and functional composite materials. Two key aspects of graphene's mechanical behavior are its elastic and adhesive properties.
Cesar Chialvo, D. Z. Rocklin, Kelly B. T., Landau L. D., Mindlin R. D., Nadya Mason, Paul M. Goldbart, Richard L. Weaver, Scott Scharfenberg   +8 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Behavioral Mechanisms Underlying Nicotine Reinforcement [PDF]

, 2015
Cigarette smoking is the leading cause of preventable deaths worldwide, and nicotine, the primary psychoactive constituent in tobacco, drives sustained use. The behavioral actions of nicotine are complex and extend well beyond the actions of the drug as a primary reinforcer.
Laura E, Rupprecht, Tracy T, Smith, Rachel L, Schassburger, Deanne M, Buffalari, Alan F, Sved, Eric C, Donny   +5 more
openaire   +2 more sources

Time-independent Anisotropic Plastic Behavior by Mechanical Subelement Models [PDF]

, 1983
The paper describes a procedure for modelling the anisotropic elastic-plastic behavior of metals in plane stress state by the mechanical sub-layer model.
Pian, T. H. H.
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Unlocking the black box beyond Bayesian global optimization for materials design using reinforcement learning

npj Computational Materials
Materials design often becomes an expensive black-box optimization problem due to limitations in balancing exploration-exploitation trade-offs in high-dimensional spaces.
Yuehui Xian, Xiangdong Ding, Xue Jiang, Yumei Zhou, Jun Sun, Dezhen Xue, Turab Lookman   +6 more
doaj   +1 more source

Parasite-Induced Behavioral Change: Mechanisms [PDF]

, 2010
Animal behavior and parasitism are more tightly linked than commonly thought. One of the most astonishing phenomena in host–parasite antagonistic interactions is ‘host manipulation,' that is, the ability of a parasite to alter the behavior of its host in ways that appear to increase parasite fitness at the expense of host fitness.
Perrot-Minnot, Marie-Jeanne, Cézilly, Frank   +1 more
openaire   +2 more sources