Results 91 to 100 of about 441,732 (325)

Mechanical Circulatory Support for Massive Pulmonary Embolism

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Up to 50% of patients with pulmonary embolism (PE) experience hemodynamic instability and approximately 70% of patients who die of PE experience an accelerated cascade of symptoms within the first hours of onset of symptoms, thus necessitating rapid ...
Salman Abdulaziz, Vivek Kakar, Praveen G. Kumar, Ibrahim Fawzy Hassan, Alain Combes, Daniel Brodie, Nicholas A. Barrett, Jack Tan, Saleh Fares Al Ali   +8 more
doaj   +1 more source

Feasibility of transfemoral hepatic vein/wedged portal venous pressure measurement in total artificial heart

Radiology Case Reports, 2017
The development of technology and limitation of numerous ventricular assist devices has increased usage of the total artificial heart (TAH) for mechanical circulatory support.
Ashwani Kumar Sharma, MD, Jonathan Huang, DO, Himabindu Vidula, MD, MS, FACC, Jeffrey Alexis, MD, Juan M. Lehoux, MD   +4 more
doaj   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Safe Placement of Temporary Left Ventricular Assist Device Using Monitored Anesthesia Care and Regional Anesthesia in Patients With Cardiogenic Shock

JACC: Case Reports, 2023
Patients with advanced cardiogenic shock requiring mechanical circulatory support are uniquely susceptible to clinical deterioration. Limiting physiologic perturbations via avoidance of general anesthesia and endotracheal intubation by awake Impella 5.5 ...
John DePaolo, MD, PhD, Amit Iyengar, MD, MSE, Samuel Cohen, MD, MS, John J. Kelly, MD, Audrey E. Spelde, MD, Joyce Wald, DO, Emily J. Mackay, DO, MS, Michael Ibrahim, MBBS, PhD, Asad A. Usman, MD, Marisa Cevasco, MD, MPH   +9 more
doaj  

MECHANICAL CIRCULATORY SUPPORT: PROBLEMS, SOLUTIONS AND NEW DIRECTIONS

Вестник трансплантологии и искусственных органов, 2014
The article brings up for the discussion main problems standing in the way of development of the mechanical circulatory support (MCS) technology. We give a short historical overview of the development of this technology in our country. Classifi cation of
G. P. Itkin
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

The roles and applications of extracellular vesicles in cancer

Molecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Platelet morphology in patients with mechanical circulatory support [PDF]

, 1997
Oliver Dewald
openalex   +1 more source

Data-Driven Simulator for Mechanical Circulatory Support with Domain Adversarial Neural Process [PDF]

arXiv
Mechanical Circulatory Support (MCS) devices, implemented as a probabilistic deep sequence model. Existing mechanical simulators for MCS rely on oversimplifying assumptions and are insensitive to patient-specific behavior, limiting their applicability to real-world treatment scenarios.
arxiv