Results 181 to 190 of about 69,669 (298)

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

When NOT to use short-term mechanical circulatory supportCentral Message

JTCVS Open, 2020
Vivek Rao, MD, PhD, Fillio Billia, MD, PhD   +1 more
doaj  

Pediatric Mechanical Circulatory Support

, 2005
Brian W. Duncan
openalex   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Mechanical Circulatory Support in Pediatric Patients with the MEDOS Assist Device

, 2005
Ingo Kaczmarek, Joerg S. Sachweh, J Groetzner, H Gulbins, Helmut Mair, Kozlik-Feldmann Rainer, Stefanie Zysk, Bruno Reichart, Sabine Daebritz   +8 more
openalex   +1 more source

Leukocyte Expression Analysis of the Systemic Inflammatory Response to Mechanical Circulatory Support Device Implantation [PDF]

, 2008
Anshu Sinha, F. Latif, Khurram Shahzad, Martín Cadeiras, Manuel von Bayern, Simin Oz, Mario C. Deng   +6 more
openalex   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Management of Intracranial Hemorrhage in Patients with Mechanical Circulatory Support: A Role for Low-Molecular-Weight Heparins?

, 2005
Emmanuelle Vermès, Matthias Kirsch, Titi Farrokhi, Bernadette Boval, Eliane Melon, D Loisance, Ludovic Drouet   +6 more
openalex   +1 more source

Outcomes of the Fifth International Conference on Pediatric Mechanical Circulatory Support Systems & Pediatric Cardiopulmonary Perfusion [PDF]

, 2009
Akif Ündar
openalex   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source