Results 131 to 140 of about 1,128,815 (309)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Mechanical Engineering Annual Assessment Report to the College 2008-2009
, 2013 Describes the Mechanical Engineering assessment activities for the academic year 2008-2009The Mechanical Engineering annual assessment report to the College for the Office of Academic Assessment.The report details activities related to the department's 6
California State University, Northridge. Department of Mechanical Engineering
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Mechanical Engineering Annual Assessment Report to the College 2007-2008
, 2013 Describes the Mechanical Engineering assessment activities for the academic year 2007-2008The Mechanical Engineering annual assessment report to the College for the Office of Academic Assessment.
California State University, Northridge. Department of Mechanical Engineering
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Journal of Applied Linguistics and Literature, 2018 This research was aimed to know the appropriate assessment, find out speaking’s authentic assessment material and find out the characteristics of authentic speaking assessment model for Mechanical Engineering of Vocational School.
Erlian Dwisnu +2 more
doaj +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Modeling the performance of the piston ring-pack in internal combustion engines
, 1997 Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1997.Includes bibliographical references (leaves 186-194).by Tian Tian.Ph ...
Tian, Tian (Scientist in Mechanical Engineering)
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Mechanical Engineering 2016 Annual Report
, 2016 The 2016 Annual Report for the Dept. of Mechanical Engineering at Virginia Tech. This issue contains demographic information, a faculty list and a partial list of laboratories within the ME ...
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Mechanical and Aerospace Engineering (MAE) Home [PDF]
, 2014 Mechanical and Aerospace Engineering Department at the Naval Postgraduate School website homepage.Web page capture on this date: 2014-05 ...
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