Results 161 to 170 of about 1,128,815 (309)

Assessment model for multivariable fatigue performance of EA4T axles containing defects : ^a School of mechanical Engineering, Chengdu University, Chengdu 610,106, China. [PDF]

Sci Rep
Luo Y, Li G, Qi C, Li C, Hu Y.
europepmc   +1 more source

Engineering Mechanics Engineering Kinematics [PDF]

Nature, 1942
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Bio-inspired designs: leveraging biological brilliance in mechanical engineering-an overview. [PDF]

3 Biotech
Fattepur G, Patil AY, Kumar P, Kumar A, Hegde C, Siddhalingeshwar IG, Kumar R, Khan TMY.   +7 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Research on the maker learning experiences of engineering college students majoring in mechanical engineering in China. [PDF]

Sci Rep
Yang W, Chen P.
europepmc   +1 more source

Application of Peter Chew Method in Mechanical Engineering (Jib Crane)

, 2023
Chew P.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Scalability of carbon-neutral cooling system

, 2019
Thesis: S.B., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2019Cataloged from the official PDF of thesis.Includes bibliographical references (page 26).The scalability of a carbon neutral cooling system to provide the MIT ...
Noh, Christine (Researcher in mechanical engineering).
core  

The role of generative AI tools in shaping mechanical engineering education from an undergraduate perspective. [PDF]

Sci Rep
Akolekar H, Jhamnani P, Kumar V, Tailor V, Pote A, Meena A, Kumar K, Challa JS, Kumar D.   +8 more
europepmc   +1 more source