Results 201 to 210 of about 5,065,932 (329)

Teaching Method of Mechanical Design and Engineering Graphics(Special Issue on Engineering Education)

, 1972
G. Takeshi Sato
openalex   +2 more sources

A review of origami applications in mechanical engineering

, 2016
Nicholas Turner, B. Goodwine, M. Sen
semanticscholar   +1 more source

Only the strong survive: therapeutic selective pressure drives medulloblastoma leptomeningeal metastasis

Molecular Oncology, EarlyView.
Radiation therapy induces cancer cell death and immune cell infiltration, mainly monocytes, macrophages, and dendritic cells. Elevated serum cytokine levels and disruption of the blood–brain barrier promote leptomeningeal dissemination. Cotreatment with dexamethasone reduces cytokine levels, preserves barrier integrity, and limits metastatic spread ...
Francis Y. He, Adrienne Boire
wiley   +1 more source

Thinking about the Future of Mechanical Engineering and Machine Industries(Creative Reflections in Science and Technology)

, 1972

openalex   +2 more sources

Complex systems in mechanical engineering

Advances in Mechanical Engineering, 2017
JA Tenreiro Machado, António M Lopes
doaj   +1 more source

Author Correction: Optimizing ternary hybrid nanofluids using neural networks, gene expression programming, and multi-objective particle swarm optimization: a computational intelligence strategy. [PDF]

Sci Rep
Hai T, Basem A, Alizadeh A, Singh PK, Rajab H, Maatki C, Becheikh N, Kolsi L, Singh NSS, Maleki H.   +9 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Safety in Railway Operation(<Special Issue>the Technology for Safety in Mechanical Engineering)

, 1975
Masahiro SHINTAKU
openalex   +2 more sources

Mechanical characterization of sisal fiber-groundnut shell powder reinforced epoxy composites. [PDF]

Sci Rep
Kumar KS, Srinivasan RG, Palani S, Čep R, Salunkhe S, Nasr EA.   +5 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source