Results 241 to 250 of about 2,534,317 (363)
FEBS Open Bio, EarlyView.IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He +5 more
wiley +1 more source
On the Publication of the Special Number on Reliability of Mechanical Engineering
, 1971 Taro Shimogo, Hiroyuki Okamura
openalex +2 more sources
A potential tumor suppressor role of PLK2 in glioblastoma
FEBS Open Bio, EarlyView.PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia +5 more
wiley +1 more source
Complex systems in mechanical engineering
Advances in Mechanical Engineering, 2017 JA Tenreiro Machado, António M Lopes
doaj +1 more source
Safety in Railway Operation(<Special Issue>the Technology for Safety in Mechanical Engineering)
, 1975 Masahiro SHINTAKU
openalex +2 more sources
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
The Club of Rome and Developments in Mechanical Engineering
, 1974 Saburō Ōkita
openalex +2 more sources
ME-EM eNewsBrief, June 2023 [PDF]
, 2023 Department of Mechanical Engineering-Engineering Mechanics, Michigan Technological University
core +1 more source
FEBS Open Bio, EarlyView.We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang +7 more
wiley +1 more source