Results 11 to 20 of about 7,887 (176)

Mechanical esophageal deviation: an approach for pulmonary vein reconnection attributed to esophageal heating [PDF]

HeartRhythm Case Reports, 2016
Jorge G. Panizo, MD, Jacob S. Koruth, MD, Vivek Y. Reddy, MD   +2 more
doaj   +6 more sources

Prevention of Esophageal Damage During Ablation of Atrial Fibrillation by the Esophagus Mechanical Deviation

Journal of Cardiac Arrhythmias, 2020
Atrial fibrillation is the most prevalent arrhythmia in the world population. Despite the use of antiarrhythmics, it is difficult to control clinically, causing symptoms and mainly generating risk of a thromboembolic event.
Enrique Indalécio Pachón Mateos, José Carlos Pachón Mateos Mateos, Ricardo Carneiro Amarante, Carlos Thiene Cunha Pachón, Tasso Júlio Lobo, Tomás Guillermo Santillana Peña, Juán Carlos Zerpa Acosta, Juán Carlos Pachón Mateos, Felipe Ortêncio, Christian Higuti   +9 more
doaj   +7 more sources

Esophageal deviation using the transesophageal echocardiography probe during atrial fibrillation radiofrequency ablation: a prospective observational study [PDF]

Frontiers in Cardiovascular Medicine
BackgroundEsophageal injury is a recognized complication of atrial fibrillation (AF) radiofrequency ablation, during pulmonary vein isolation (PVI) or posterior wall ablation. Mechanical esophageal deviation has emerged as a promising preventive strategy,
Fabien Squara, Fabien Squara, Sok-Sithikun Bun, Sok-Sithikun Bun, Camille Verdan, Didier Scarlatti, Emile Ferrari   +6 more
doaj   +2 more sources

The Extent of Mechanical Esophageal Deviation to Avoid Esophageal Heating During Catheter Ablation of Atrial Fibrillation

JACC: Clinical Electrophysiology, 2017
This study sought to determine the extent of lateral esophageal displacement required during mechanical esophageal deviation (MED) and to eliminate luminal esophageal temperature elevation (LETElev) during pulmonary vein (PV) isolation.MED is a conceptually attractive strategy of minimizing esophageal injury while allowing uninterrupted energy delivery
Chandrasekar, Palaniswamy, Jacob S, Koruth, Alexander J, Mittnacht, Marc A, Miller, Subbarao, Choudry, Rahul, Bhardwaj, Dinesh, Sharma, Jonathan M, Willner, Sujata S, Balulad, Elizabeth, Verghese, Georgios, Syros, Anurag, Singh, Srinivas R, Dukkipati, Vivek Y, Reddy   +13 more
openaire   +4 more sources

Design of a Novel Haptic Joystick for the Teleoperation of Continuum-Mechanism-Based Medical Robots

Robotics, 2023
Continuum robots are increasingly used in medical applications and the master–slave-based architectures are still the most important mode of operation in human–machine interaction.
Yiping Xie, Xilong Hou, Shuangyi Wang
doaj   +1 more source

Surface EMG-based quantification of inspiratory effort: a quantitative comparison with P es

Critical Care, 2021
Background Inspiratory patient effort under assisted mechanical ventilation is an important quantity for assessing patient–ventilator interaction and recognizing over and under assistance. An established clinical standard is respiratory muscle pressure $$
Jan Graßhoff, Eike Petersen, Franziska Farquharson, Max Kustermann, Hans-Joachim Kabitz, Philipp Rostalski, Stephan Walterspacher   +6 more
doaj   +1 more source

Nasogastric administration of lenvatinib solution in a mechanically ventilated patient with rapidly growing anaplastic thyroid cancer

Endocrinology, Diabetes & Metabolism Case Reports, 2020
A 54-year-old woman was referred to our hospital with a cervical tumor. CT revealed a cervical tumor extending to the upper mediastinum, tracheal deviation and tumor infiltration in the cervical vessels.
Fumiaki Kawano, Tadato Yonekawa, Hideki Yamaguchi, Nobuhiro Shibata, Kousei Tashiro, Makoto Ikenoue, Shun Munakata, Kazuhiro Higuchi, Hiroyuki Tanaka, Yuichiro Sato, Ayumu Hosokawa, Shinsuke Takeno, Kunihide Nakamura, Atsushi Nanashima   +13 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source