Papain-based gel for biochemical caries removal: influence on microtensile bond strength to dentin
This study investigated the influence of a papain-based gel (Papacárie) for chemo-mechanical caries removal on bond strength to dentin. Human molars were assigned to the following groups: Group 1: sound teeth were flattened to expose dentin; Group 2 ...
Evandro Piva +5 more
doaj +1 more source
Coupled THM analysis of long-term anisotropic convergence in the full-scale micro tunnel excavated in the Callovo-Oxfordian argillite [PDF]
The main purpose of this paper is to analyse the convergence measurements of the ALC1604 in situ heating test carried out in the Callovo-Oxfordian claystone formation (COx) in the Meuse/Haute-Marne underground research laboratory (MHM URL).
Bumbieler, F. +4 more
core +1 more source
Arguments for a "U.S. Kamioka": SNOLab and its Implications for North American Underground Science Planning [PDF]
We argue for a cost-effective, long-term North American underground science strategy based on partnership with Canada and initial construction of a modest U.S. Stage I laboratory designed to complement SNOLab.
Aalseth +22 more
core +1 more source
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Combined Theoretical and Experimental Analysis of Mechanical Rock Salt Cutting and Cutting Tool Characteristics [PDF]
This paper investigates the mechanical cutting of rock salt with the aim of determining the cutting characteristics relevant to the optimization of cutting machine performance.
Andrei Andraș +2 more
doaj +1 more source
The behaviour of a two-component backfilling grout used in a Tunnel-Boring Machine [PDF]
The instantaneous filling of the annulus that is created behind the segment lining at the end of the tail during the TBM advance is an operation of paramount importance.
Borio, Luca +2 more
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
USING NON-BLASTING TECHNOLOGIES FOR DESTRUCTION OF HARD ROCK IN SURFACE MINING [PDF]
Determination the effective application field of non-blasting technology and technologies for the hard rock preparation for excavation during surface ...
DREBENSTEDT, Carsten +2 more
core
TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
In this study, a series of unrelieved cutting tests was conducted to analyze the effect of joints on rock cutting using a conical pick. The tests were performed on jointed rock mass specimens with joint spacings (Js) of 30, 60, and 90 mm and at cutting ...
Han-Eol Kim +4 more
doaj +1 more source

