Results 71 to 80 of about 2,521,798 (304)

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

Modeling of ground excavation with the particle finite element method [PDF]

, 2010
The present work introduces a new application of the Particle Finite Element Method (PFEM) for the modeling of excavation problems. PFEM is presented as a very suitable tool for the treatment of excavation problem.
Oñate Ibáñez de Navarra, Eugenio, Suárez Arroyo, Benjamín, Carbonell Puigbó, Josep Maria   +2 more
core   +1 more source

Novel Foraging Mechanisms in Atypical Excavate Flagellates

Journal of Eukaryotic Microbiology
ABSTRACTMost excavates, a paraphyletic assemblage of flagellates, typically present an active vaned flagellum that drives a feeding current through a ventral groove for predation. However, some have “atypical” morphologies. Here, we describe the foraging mechanisms in heteroloboseid flagellates (Discoba) that have a groove but lack the seemingly ...
Sei Suzuki‐Tellier, Alastair G. B. Simpson, Thomas Kiørboe   +2 more
openaire   +2 more sources

Finite Element Analysis of an Electro-Mechanical Knee Loading Device

, 2016
The mechanical loading of knee is an effective regimen for treatment of bone related ailments like fractures, osteoarthritis, and osteoporosis [1–2]. Efficacy of knee loading is evident from the previous studies done on rodents and other small animals [3]
Sai Krishna Prabhala, Chien, Stanley, Yokota, Hiroki, Hiroki Yokota, Sohel Anwar, Stanley Chien, Prabhala, Sai Krishna, Anwar, Sohel   +7 more
core   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

Advanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang, Chuanzan Zhou, Jiaoyan He, Pengpeng Huang, Rong Zhang, Huan Hu, Meng Jiao, Linyi Hu, Feng Liu, Xiaolong Qi, Xiang He, Yunkai Yang, Y Eugene Chinn, Dechao Feng, Dahong Zhang, Qi Zhang   +15 more
wiley   +1 more source

Too Complex to Choose? The Role of Heuristics in Shaping Farmers' Willingness to Pay for Income Stabilization Tool in Italy

Agribusiness, EarlyView.
ABSTRACT European agriculture is increasingly exposed to economic instability driven by extreme weather events, market volatility, and geopolitical tensions. To manage these growing risks, farmers are encouraged to adopt innovative risk management strategies such as the Income Stabilization Tool (IST), which offers protection against severe income ...
Alice Stiletto, Ruggiero Rippo, Samuele Trestini, Elisa Giampietri, Roberta Raffaelli, Simone Cerroni   +5 more
wiley   +1 more source

Investigation on the Mechanical Characteristics of the Excavation of a Double-Line Highway Tunnel Underpass Existing Railway Tunnel under the Influence of Dynamic and Static Load

Applied Sciences
Research on the excavation mechanical properties of underpass tunnels has already had certain results, but only a few of them consider the effects of dynamic and static loads on the excavation mechanical properties of underground tunnels at the same time;
Yifan Li, Changfu Huang, Hongjian Lu, Chao Mou   +3 more
doaj   +1 more source

Construction Optimization of Shallow Railway Tunnels under Unsymmetrical Pressure for Reducing Blasting Over-excavation

Chengshi guidao jiaotong yanjiu
Objective Over-excavation in tunnel construction, mainly caused by inappropriate blasting,will affect the smooth progress and safety of tunnel excavation, increase construction cost and reduce economic benefits.
YUAN Fengjie, WANG Haoqian, SONG Guanping, YUAN Lang, GAO Hang, XU Qianwei   +5 more
doaj   +1 more source

Toward a Behavioral Reserve Model in Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective Behavioral impairment is common in amyotrophic lateral sclerosis (ALS) and strongly affects autonomy, caregiver burden, and outcomes, yet predictors of vulnerability remain unclear. We investigated whether premorbid regulatory traits and socio‐educational exposures are associated with behavioral phenotypes in ALS within a behavioral reserve ...
Francesca Palumbo, Barbara Iazzolino, Cristina Moglia, Umberto Manera, Enrico Matteoni, Sara Cabras, Giorgio Pellegrino, Emilio Minerva, Vita Passidomo, Rosario Vasta, Gabriele Mora, Fabrizio D’Ovidio, Antonio Canosa, Andrea Calvo, Adriano Chiò   +14 more
wiley   +1 more source

EFFECT OF CHEMO-MECHANICAL CARIES REMOVAL WITH BRIX 3000 ON CHILDREN'S BEHAVIOUR DURING DENTAL TREATMENT [PDF]

Journal of IMAB
Purpose. To evaluate children's behaviour using the Frankl scale during the treatment of dentin carious lesions (code 05 according to ICDAS II) on primary molars, using chemo-mechanical excavation with Brix 3000. Material. The study included 57 children
Zornitsa Lazarova
doaj   +1 more source