Results 191 to 200 of about 229,880 (366)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Citrus Mechanical Harvesting Systems--Trunk Shakers

, 2014
Fritz Roka, Reza Ehsani, Stephen H. Futch, Barbara R. Hyman   +3 more
openalex   +2 more sources

TRELLISING TO IMPROVE MANUAL HARVEST EFFICIENCY AND TO ENABLE MECHANICAL HARVEST OF RUBUS FOR FRESH FRUIT MARKETS.. [PDF]

, 1990
Herbert D. Stiles
openalex   +1 more source

Stretchable Conductive-Ink-Based Wrinkled Triboelectric Nanogenerators for Mechanical Energy Harvesting and Self-Powered Signal Sensing

, 2022
Weitong Wu, Yapeng Shi, Yu Xiao, Jinzi Sun, Linlin Li, Yun Xu, Shaochun Zhang, Kai Dong, Lili Wang   +8 more
openalex   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

MECHANICAL HARVESTING OF COFFEE IN HIGH SLOPE

, 2018
F. Santinato, ROUVERSON PEREIRA DA SILVA, VANTUIR DE ALBUQUERQUE SILVA, CARLOS DIEGO DA SILVA, Tiago de Oliveira Tavares   +4 more
openalex   +2 more sources

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

CsEXL3 regulate mechanical harvest-related droopy leaves under the transcriptional activation of CsBES1.2 in tea plant. [PDF]

Hortic Res
Liu H, Duan L, Ma J, Jin J, Huang R, Liu Y, Chen S, Xu X, Chen J, Yao M, Chen L.   +10 more
europepmc   +1 more source

Healable and shape-memory dual functional polymers for reliable and multipurpose mechanical energy harvesting devices [PDF]

, 2019
Wei Xu, Man‐Chung Wong, Qiongyu Guo, Tiezheng Jia, Jianhua Hao   +4 more
openalex   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source