Results 201 to 210 of about 229,880 (366)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Incidence and pathophysiology of gastrointestinal bleeding during mechanical circulatory support: A retrospective analysis using machine learning algorithms. [PDF]

J Extra Corpor Technol
Gore K, Linder D, Duque JJM, Wang J, Rudnicki C, Alexis Ruiz A, Yockelson S, Nossaman B.   +7 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Optimizing Vibratory Sorting Machine of Crickets: Effects of Surface Friction, Oscillation Dynamics, and Energy Consumption. [PDF]

Insects
Duangchanchote A, Saenkham S, Suraporn S, Zainuddin A, Cansee S.   +4 more
europepmc   +1 more source

An evolutionary economic perspective on technical change and adjustment in cane harvesting systems in the Australian sugar industry [PDF]

Australian sugar-producing regions have differed in terms of the extent and rate of incorporation of new technology into harvesting systems. The Mackay sugar industry has lagged behind most other sugar-producing regions in this regard.
Brennan, Lisa E., Wegener, Malcolm K.
core   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source

Short communication: performance of beef cows fed Kernza intermediate wheatgrass straw mixed with alfalfa haylage. [PDF]

Transl Anim Sci
Pizarro DM, Crooks A, Wattiaux MA, Picasso VD.   +3 more
europepmc   +1 more source

Comparison of the yielding of plum, sour cherry, and sweet cherry trees trained to a trellis for mechanical harvesting of fruit with those trained to a leader

, 2023
Z. Buler, J. Rabcewicz, Paweł Bialkowski   +2 more
openalex   +2 more sources

Reduction of Oxide Inclusions During the High‐Frequency Welding of Steel via a Nonthermal Ar/H2 Plasma Jet

Advanced Engineering Materials, EarlyView.
High‐frequency (HF) welding of steel is limited by oxide inclusions that degrade weld quality. This study demonstrates, for the first time, the integration of a nonthermal Ar/H2 dielectric barrier discharge (DBD) plasma jet into HF welding. Local plasma treatment provides effective shielding and in‐situ oxide reduction, resulting in markedly fewer and ...
Viktor Udachin, Lienhard Wegewitz, René Gustus, Henning Wiche, Wolfgang Maus‐Friedrichs   +4 more
wiley   +1 more source

Risk for sepsis during mechanical circulatory support★. [PDF]

J Extra Corpor Technol
Gore K, Linder D, Duque JJM, Wang J, Baguley J, Kolesnikowicz C, Yockelson S, Singh M, Ruiz AA, Nossaman BD.   +9 more
europepmc   +1 more source