Results 51 to 60 of about 43,427 (229)

Pepper Harvest Mechanism

, 2020
Due to increased food need, plant cultivation issue has started to come up more often. As in all stagesof plant cultivation, the importance of harvesting is also increasing. Due to the consequences of shifting theworkforce to different areas in the developing world, tools and machines manufactured for use in agricultureneed to be mechanized with ...
Tekgüler, Ali, Karaköse, Tuğba
openaire   +1 more source

Comparison between Manual Harvesting and Mechanical Harvesting

Journal of Scientific Research and Reports
This paper presents a thorough analysis of the differences between human and automated harvesting techniques in agriculture, including their categorization, impacts, difficulties, costs, and potential future developments. Manual harvesting, which involves labor-intensive methods, enables meticulous handling and yields top-notch product.
Pargi Sanjay J., Pankaj Gupta, P. R. Balas, V. U. Bambhaniya   +3 more
openaire   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Date harvest mechanization

California Agriculture, 1966
Research started in 1961 by agricultural engineers of USDA and University of California has led to commercial acceptance of mechanical harvesting methods with resulting labor and cost savings for California date growers. About 65% of the 1965–66 date crop is expected to be harvested with the aid of various mechanical systems that can reduce labor ...
R Perkins, G Brown
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Over-the-Row Mechanical Harvest of Cider Apples (Malus domestica Borkh.)

Horticulturae
The single greatest annual production cost for an established cider apple (Malus domestica Borkh.) orchard is the labor required to hand harvest. Reducing harvest labor time may increase the appeal and profitability of growing cider apples.
Seth Brawner, Aidan Kendall, Lee Kalcsits, Carol Miles   +3 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Harvesting Method Affects Water Dynamics and Yield of Sweet Orange with Huanglongbing

Agriculture, 2018
Changes in grove management practices may change crop water dynamics. The objective of this study was to estimate sap flow, stem water potential (Ψstem), and citrus yield as affected by harvesting methods in sweet orange (Citrus sinensis) trees affected ...
Said A. Hamido, Kelly T. Morgan
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Mechanical aids to sweet potato harvest

California Agriculture, 1969
APPROXIMATELY 9,000 acres of sweet potatoes are grown annually in California, with Merced County accounting for more than 60 per cent of this total acreage. Fresno, Stanislaus, San Joaquin, and Kern counties grow the remaining 40 per cent of the acreage.
M Zahara, R Scheuerman
doaj